A-740003

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Names

[ CAS No. ]:
861393-28-4

[ Name ]:
A-740003

[Synonym ]:
N-{1-[N''-Cyano-N'-(quinolin-5-yl)carbamimidamido]-2,2-dimethylpropyl}-2-(3,4-dimethoxyphenyl)acetamide
N-(1-{(E)-[(Cyanoamino)(5-quinolinylamino)methylene]amino}-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide
cc-516
UNII:532OV6WA05
Benzeneacetamide, N-[1-[[(1E)-(cyanoamino)(5-quinolinylamino)methylene]amino]-2,2-dimethylpropyl]-3,4-dimethoxy-
CS-0297
A-740003

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C26H30N6O3

[ Molecular Weight ]:
474.555

[ Exact Mass ]:
474.237946

[ PSA ]:
120.66000

[ LogP ]:
2.77

[ Index of Refraction ]:
1.597

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

Synthetic Route

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Precursor & DownStream

Precursor

  • N-[1-(1H-Benzotriazol-1-yl)-2,2-dimethylpropyl]-3,4-dimethoxybenzeneacetamide
  • N-Cyano-N'-5-quinolinylguanidine

DownStream

Articles

Disruption in connexin-based communication is associated with intracellular Ca²⁺ signal alterations in astrocytes from Niemann-Pick type C mice.

PLoS ONE 8 , e71361, (2013)

Reduced astrocytic gap junctional communication and enhanced hemichannel activity were recently shown to increase astroglial and neuronal vulnerability to neuroinflammation. Moreover, increasing evide...


More Articles

Related Compounds

  • A-943931 dihydrochloride
  • 1-(Imidazo[1,2-a]pyridin-3-yl)ethanol
  • a-D-ribo-Hexopyranoside, methyl2,6-dideoxy-, dibenzoate (9CI)
  • a-D-erythro-Hex-2-enopyranoside,methyl 2,3-dideoxy-4,6-O-(phenylmethylene)- (9CI)
  • a-Methyl-3-pyrrolidinemethanol HCl
  • a-D-Xylopyranosyl chloride,triacetate (9CI)