tert-Butyl carbazate

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Names

[ CAS No. ]:
870-46-2

[ Name ]:
tert-Butyl carbazate

[Synonym ]:
Carbazic acid tert-butyl ester
tert-Butyl carbazate
tert-Butyloxycarbonylhydrazide
Hydrazinecarboxylic acid, 1,1-dimethylethyl ester
t-butyl carbazate
tert-butyl N-aminocarbamate
T-BUTYLCARBAZATE
EINECS 212-795-3
tert-Butylhydrazincarboxylat
MFCD00007593
2-Methyl-2-propanyl hydrazinecarboxylate
tert-butyl hydrazinecarboxylate
tert-Butylcarbazate

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
303.6±0.0 °C at 760 mmHg

[ Melting Point ]:
39-42 °C(lit.)

[ Molecular Formula ]:
C5H12N2O2

[ Molecular Weight ]:
132.161

[ Flash Point ]:
91.7±0.0 °C

[ Exact Mass ]:
132.089874

[ PSA ]:
64.35000

[ LogP ]:
0.44

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.449

[ Storage condition ]:
Store at RT.

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R24/25;R36/37/38;R48

[ Safety Phrases ]:
S45-S36/37/39-S16

[ RIDADR ]:
1325

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
4.1

[ HS Code ]:
29280090

Synthetic Route

Precursor & DownStream

Precursor

  • Di-tert-butyl dicarbonate
  • tert-Butyl phenyl carbonate
  • Trichloroacetic acid tert-butyl ester
  • tert-butyl methylsulfanylformate
  • tert-Butyl acetoacetate
  • tert-butyl cyanoformate
  • benzyl tert-butyl carbonate
  • Carbamic acid, nitro-, 1,1-dimethylethyl ester (9CI)
  • tert-Butyl carbamate

DownStream

  • N-Boc-O-tosyl hydroxylamine
  • Carbonazidic acid,1,1-dimethylethyl ester
  • 3-Iodobenzhydrazide
  • Boc-D-Glutamic acid 5-benzylester
  • 1-Boc-4-Methylpiperazine
  • 1-Benzyl 2-(tert-butyl) 1,2-hydrazinedicarboxylate
  • tert-Butyl hydroxycarbamate
  • Boc-D-Glu-NH2
  • 1-BOC-PYRAZOLIDINE
  • tert-Butyl 1H-pyrrol-1-ylcarbamate

Customs

[ HS Code ]: 29280090

Articles

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AAPS J. 16(6) , 1185-93, (2014)

Presentation of antigen with immune stimulating "signal" has been a cornerstone of vaccine design for decades. Here, the antigen plus immune "signal" of vaccines is modified to produce antigen-specifi...

Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.

Eur. J. Pharm. Sci. 58 , 1-12, (2014)

In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (H...

Hyaluronic acid-tumor necrosis factor-related apoptosis-inducing ligand conjugate for targeted treatment of liver fibrosis.

Acta Biomater. 12 , 174-82, (2014)

Liver fibrosis is a chronic liver disease caused by viral infection and/or metabolic, genetic and cholestatic disorders. The inhibition of hepatic stellate cell (HSC) activation and the selective apop...


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Related Compounds

  • tert-butyl carbazate
  • 3-(MALEIMIDOPROPANE-1-CARBONYL-1-(TERT-BUTYL)CARBAZATE
  • 4-(MALEIMIDOMETHYL)CYCLOHEXANE-1-CARBONYL-1-(TERT-BUTYL)CARBAZATE
  • tert-butyl 2-(diphenylmethylene)hydrazinecarboxylate
  • TERT-BUTYL 2-(PROPAN-2-YLIDENE)HYDRAZINECARBOXYLATE
  • 2-Methyl-2-propanyl 2-(4-cyanobenzyl)hydrazinecarboxylate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-Tert-butyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 2-(4-Aminobutyl)-1,3-dioxolane