tert-Butyl carbazate

tert-Butyl carbazate Structure
tert-Butyl carbazate structure
Common Name tert-Butyl carbazate
CAS Number 870-46-2 Molecular Weight 132.161
Density 1.0±0.1 g/cm3 Boiling Point 303.6±0.0 °C at 760 mmHg
Molecular Formula C5H12N2O2 Melting Point 39-42 °C(lit.)
MSDS Chinese USA Flash Point 91.7±0.0 °C

Structure, size, and solubility of antigen arrays determines efficacy in experimental autoimmune encephalomyelitis.

AAPS J. 16(6) , 1185-93, (2014)

Presentation of antigen with immune stimulating "signal" has been a cornerstone of vaccine design for decades. Here, the antigen plus immune "signal" of vaccines is modified to produce antigen-specific immunotherapies (antigen-SITs) that can potentially repro...

Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours.

Eur. J. Pharm. Sci. 58 , 1-12, (2014)

In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly ...

Hyaluronic acid-tumor necrosis factor-related apoptosis-inducing ligand conjugate for targeted treatment of liver fibrosis.

Acta Biomater. 12 , 174-82, (2014)

Liver fibrosis is a chronic liver disease caused by viral infection and/or metabolic, genetic and cholestatic disorders. The inhibition of hepatic stellate cell (HSC) activation and the selective apoptosis of activated HSCs can be a good strategy to treat liv...

Palladium-catalyzed cross-coupling between vinyl halides and tert-butyl carbazate: first general synthesis of the unusual N-Boc-N-alkenylhydrazines.

Org. Lett. 9 , 275, (2007)

N-Boc-N-alkenylhydrazines, an almost unknown type of compounds, have been prepared with high to moderate yields via palladium-catalyzed cross-coupling between alkenyl halides and tert-butyl carbazate. The present methodology represents the first general way t...

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