Diphenyl disulfide

Names

[ CAS No. ]:
882-33-7

[ Name ]:
Diphenyl disulfide

[Synonym ]:
MFCD00003065
1,1'-Disulfanediyldibenzene
Disulfide, diphenyl
(phenyldisulfanyl)benzene
Diphenyl disulfide
EINECS 212-926-4
diphenyldisulfide
Phenyl disulfide

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
310.0±11.0 °C at 760 mmHg

[ Melting Point ]:
58-60 °C

[ Molecular Formula ]:
C₁₂H₁₀S₂

[ Molecular Weight ]:
218.338

[ Flash Point ]:
177.8±20.8 °C

[ Exact Mass ]:
218.022385

[ PSA ]:
50.60000

[ LogP ]:
4.41

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.680

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong bases.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SS6825000

CHEMICAL NAME :: Phenyl disulfide

CAS REGISTRY NUMBER :: 882-33-7

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H10-S2

MOLECULAR WEIGHT :: 218.34

WISWESSER LINE NOTATION :: RSSR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 764 mg/kg/7D-I

TOXIC EFFECTS :: Endocrine - changes in spleen weight Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - changes in iron

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 5,414,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M5195 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 176 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H410

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
UN 3335

[ WGK Germany ]:
3

[ RTECS ]:
SS6825000

[ HS Code ]:
2930909090

Precursor & DownStream

Precursor

DownStream

Diphenylbis(phenylthio)stannane
1-methyl-4-(1-phenylsulfanylethyl)benzene
trimethyl(phenylsulfanyl)stannane
3-methoxy-2-phenylsulfanyl-2H-furan-5-one
ethyl 3-phenylsulfanyl-1H-indole-2-carboxylate
2-(phenylsulfanylmethyl)oxane
2-phenylsulfanylpyrazine
ethyl 4-phenylsulfanylbenzoate
Triphenyltrithioorthoformate
Mesityl phenyl sulfide

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Targeting the fatty acid biosynthesis enzyme, beta-ketoacyl-acyl carrier protein synthase III (PfKASIII), in the identification of novel antimalarial agents.

J. Med. Chem. 52 , 952-63, (2009)

The importance of fatty acids to the human malaria parasite, Plasmodium falciparum, and differences due to a type I fatty acid synthesis (FAS) pathway in the parasite, make it an attractive drug targe...

The fate of diphenyl sulphide, diphenyl sulphoxide and diphenyl sulphone in the rat.

Drug Metabol. Drug Interact. 16(3) , 191-206, (2000)

Radiolabelled [UL-14C]-diphenyl sulphide, [UL-14C]-diphenyl sulphoxide and [UL-14C]-diphenyl sulphone were administered by gavage (1.0 mmol/kg body weight) to adult male Wistar rats following an overn...

Functional groups and sulfur K-edge XANES spectra: divalent sulfur and disulfides.

J. Phys. Chem. A 114(35) , 9523-8, (2010)

Sulfur K-edge XANES was measured for two divalent sulfurs (dibenzyl and benzyl phenyl) and two disulfides (dibenzyl and diphenyl). The absorption spectra could be assigned using density functional the...