Diphenyl disulfide
Diphenyl disulfide structure
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Common Name | Diphenyl disulfide | ||
|---|---|---|---|---|
| CAS Number | 882-33-7 | Molecular Weight | 218.338 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 310.0±11.0 °C at 760 mmHg | |
| Molecular Formula | C12H10S2 | Melting Point | 58-60 °C | |
| MSDS | Chinese USA | Flash Point | 177.8±20.8 °C | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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Targeting the fatty acid biosynthesis enzyme, beta-ketoacyl-acyl carrier protein synthase III (PfKASIII), in the identification of novel antimalarial agents.
J. Med. Chem. 52 , 952-63, (2009) The importance of fatty acids to the human malaria parasite, Plasmodium falciparum, and differences due to a type I fatty acid synthesis (FAS) pathway in the parasite, make it an attractive drug target. In the present study, we developed and a utilized a phar... |
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The fate of diphenyl sulphide, diphenyl sulphoxide and diphenyl sulphone in the rat.
Drug Metabol. Drug Interact. 16(3) , 191-206, (2000) Radiolabelled [UL-14C]-diphenyl sulphide, [UL-14C]-diphenyl sulphoxide and [UL-14C]-diphenyl sulphone were administered by gavage (1.0 mmol/kg body weight) to adult male Wistar rats following an overnight fast. For all compounds, faeces were the major route o... |
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Functional groups and sulfur K-edge XANES spectra: divalent sulfur and disulfides.
J. Phys. Chem. A 114(35) , 9523-8, (2010) Sulfur K-edge XANES was measured for two divalent sulfurs (dibenzyl and benzyl phenyl) and two disulfides (dibenzyl and diphenyl). The absorption spectra could be assigned using density functional theory with the "half core hole" approximation for the core ho... |
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Reductive addition of the benzenethiyl radical to alkynes by amine-mediated single electron transfer reaction to diphenyl disulfide.
Org. Lett. 11(15) , 3298-301, (2009) Hydrothiolation of alkynes proceeds with diphenyl disulfide and tripropylamine. Amine-mediated single electron transfer to diphenyl disulfide can be proposed for the reaction mechanism. Applications of the method to radical cyclizations of eneyne compounds ar... |
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Molecular modeling and enzyme kinetics indicate a novel mechanism for mammalian 5-lipoxygenase.
Adv. Prostaglandin. Thromboxane. Leukot. Res. 17A , 69-74, (1987)
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Organochalcogens effects on delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro.
Toxicology 191(2-3) , 169-78, (2003) Organochalcogens are important intermediates and useful reagents in organic synthesis, which can increase human exposure risk to these chemicals in the workplace. As well, there are a number of reported cases of acute toxicity following organochalcogen ingest... |
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Suppressing effects of S-methyl methanethiosulfonate and diphenyl disulfide on mitomycin C-induced somatic mutation and recombination in Drosophila melanogaster and micronuclei in mice.
Mutat. Res. 385(1) , 41-6, (1997) S-Methyl methanethiosulfonate (MMTS) and diphenyl disulfide (DPDS) are temporary enzyme-sulfhydryl blocking agents. They are naturally occurring phytoalexin-like and synthetic substances known to be very potent bio-antimutagens in Escherichia coli B/r WP2. In... |
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Temporary anion states and dissociative electron attachment in diphenyl disulfide.
J. Phys. Chem. A 110(34) , 10219-24, (2006) The temporary anion states of gas-phase diphenyl disulfide are characterized by means of electron transmission (ET) and dissociative electron attachment (DEA) spectroscopies. The measured energies of vertical electron attachment are compared to the virtual or... |
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Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain.
Neurochem. Res. 27(4) , 297-303, (2002) Ebselen (2-phenyl- 1,2-benzisoselenazole-3 (2H)-one) is a seleno-organic compound with antioxidant properties, and anti-inflammatory actions. Recently, ebselen improved the outcome of acute ischemic stroke in humans. In the present study, the potential antiox... |
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Diphenyldisulfide inhibits indomethacin-induced ulcerogenesis in rats.
Agents Actions 21(3-4) , 314-5, (1987) Indomethacin was administered subcutaneously to rats, 4 mg/kg/day for 4 consecutive days in order to produce erosions of the small intestine which were scored at necropsy on day 5. Orally administered phenidone (up to 250 mg/kg/day), a mixed cycloocygenase-li... |