Metorphamide (free acid)

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Names

[ CAS No. ]:
88866-92-6

[ Name ]:
Metorphamide (free acid)

[Synonym ]:
TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL
METORPHINAMIDE
Adrenorphin,Free Acid
METORPHAMIDE
H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-OH
Metorphamide (free acid)

Chemical & Physical Properties

[ Molecular Formula ]:
C44H68N14O10S

[ Molecular Weight ]:
985.16400

[ Exact Mass ]:
984.49600

[ PSA ]:
436.35000

[ LogP ]:
2.99980

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

MDR1 P-glycoprotein transports endogenous opioid peptides.

Peptides 22 , 2015-2020, (2001)

MDR1 P-glycoprotein is generally regarded as an efflux pump for amphipathic toxic compounds. The question remains, however, whether certain endogenous compounds are also substrates for this transporte...

Metorphamide, a novel endogenous adrenal opioid peptide, inhibits nicotine-induced secretion from bovine adrenal chromaffin cells.

Brain Res. 363 , 10-17, (1986)

Opioid peptides are found in high concentrations in the adrenal medulla. Recently, a novel opioid octapeptide, metorphamide, possessing an amidated C-terminal, was characterized and also found to be p...

Opioid inhibition of nicotine-induced 45Ca2(+)-uptake into cultured bovine adrenal medullary cells.

Biochem. Pharmacol. 41 , 715-722, (1991)

The ability of a number of opioid agonists and antagonists to affect nicotine-induced 45Ca2(+)-uptake into cultured bovine adrenal medullary cells has been investigated. High (10 microM) concentration...


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