2,4-Dihydroxybenzoic acid

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Names

[ CAS No. ]:
89-86-1

[ Name ]:
2,4-Dihydroxybenzoic acid

[Synonym ]:
p-Hydroxysalicylic acid
b-resorcylic acid
2,4-dihydroxybenzoic_acid
4-Carboxyresorcinol
resorcylic acid
2,4-dihydroxy-benzoic acid
2,4-Dihydroxy benzoic acid
Benzoic acid, 2,4-dihydroxy-
2,4-Dihydroxybenzoic acid
2,4,6-TRIPHENYLPYRYLIUM TETRAFLUOROBORATE
Benzoic acid,2,4-dihydroxy
4-Hydroxysalicylic acid
EINECS 201-946-9
MFCD00002451
2,4-Dihydroxybenzenecarboxylic Acid

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
414.8±15.0 °C at 760 mmHg

[ Melting Point ]:
208-211 °C (dec.)(lit.)

[ Molecular Formula ]:
C7H6O4

[ Molecular Weight ]:
154.120

[ Flash Point ]:
218.8±16.9 °C

[ Exact Mass ]:
154.026611

[ PSA ]:
77.76000

[ LogP ]:
1.60

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.671

[ Water Solubility ]:
8 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VH3708050
CHEMICAL NAME :
beta-Resorcylic acid
CAS REGISTRY NUMBER :
89-86-1
BEILSTEIN REFERENCE NO. :
1946213
LAST UPDATED :
199701
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C7-H6-O4
MOLECULAR WEIGHT :
154.13

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 196,478,1976 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
642 mg/kg
SEX/DURATION :
female 11 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 38,209,1982

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
VH3708050

[ HS Code ]:
2942000000

Synthetic Route

Precursor & DownStream

Precursor

  • Resorcine
  • UNII:SJ995B41AO
  • 1-Methoxy-2-propanol
  • b-Resorcylaldehyde
  • 2,4-Dihydroxyacetophenone
  • 1,2,4-Trihydroxybenzene
  • 2,4-Dihydroxybenzyl alcohol
  • Potassium hydrogen carbonate
  • 2,4-Dimethoxybenzoicacid
  • Salicylic acid

DownStream

  • methyl 2,4-diacetyloxybenzoate
  • METHYL 2,4-DIMETHOXYBENZOATE
  • Methyl 2-methoxybenzoate
  • Methyl 3-methoxybenzoate
  • Methyl anisate
  • Methyl 3,4-dimethoxybenzoate
  • Trimethylgallic acid methyl ester
  • Benzoic acid,2,3-dimethoxy-, methyl ester
  • methyl 2,5-dimethoxybenzoate
  • Methyl 3,5-dimethoxybenzoate

Customs

[ HS Code ]: 2918290000

[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 5-BROMO-2,4-DIHYDROXYBENZOIC ACID
  • 3-amino-2,4-dihydroxybenzoic acid
  • 5-Amino-2,4-dihydroxybenzoic acid
  • 3-benzyl-2,4-dihydroxybenzoic acid
  • 5-chloro-2,4-dihydroxybenzoic acid
  • 5-acetyl-2,4-dihydroxybenzoic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
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  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine