1-(2-Fluorophenyl)methanamine

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Names

[ CAS No. ]:
89-99-6

[ Name ]:
1-(2-Fluorophenyl)methanamine

[Synonym ]:
o-Fluorobenzylamine
1-(2-Fluorophenyl)methylamine
MFCD00008107
1-(2-Fluorophenyl)methanamine
Z1R BF
(2-Fluorophenyl)methanamine
Benzenemethanamine, 2-fluoro-
EINECS 201-957-9

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
185.9±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H8FN

[ Molecular Weight ]:
125.144

[ Flash Point ]:
67.2±0.0 °C

[ Exact Mass ]:
125.064079

[ PSA ]:
26.02000

[ LogP ]:
1.14

[ Vapour Pressure ]:
0.7±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.523

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R20/21/22;R34

[ Safety Phrases ]:
S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 2735 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2921420090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Fluorobenzonitrile
  • 2-Fluorobenzaldehyde
  • 2-Fluorobenzyl bromide
  • 2-Fluorotoluene

DownStream

  • 2-Fluorobenzaldehyde
  • 2-Fluorobenzyl isothiocyanate
  • 9-[(2-fluorophenyl)methyl]-N,N-dimethylpurin-6-amine
  • (2-(diphenylphosphino)phenyl)Methanamine
  • Benzamide,2-fluoro-N-phenyl-
  • Benzothiazole,2-(2-fluorophenyl)-
  • (2-FLUOROBENZYL)GUANIDINE
  • 3-[(2-fluorophenyl)methyl]-2-phenylpyrido[2,3-d]pyrimidin-4-one
  • N-[(2-fluorophenyl)methyl]-3-methylimidazo[4,5-c]pyridin-4-amine
  • 3-[(2-fluorophenyl)methyl]-1-(2-hydroxyethyl)-1-methylthiourea

Customs

[ HS Code ]: 2921499090

[ Summary ]:
2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).

Bioorg. Med. Chem. Lett. 17 , 2171-2178, (2007)

The design, synthesis, and SAR of a series of substituted spirohydantoins are described. Optimization of an in-house screening hit gave compounds that exhibited potent binding affinity and functional ...

9-(2-Fluorobenzyl)-6-(methylamino)-9H-purine hydrochloride. Synthesis and anticonvulsant activity.

J. Med. Chem. 29(7) , 1133-4, (1986)


More Articles

Related Compounds

  • 1-Cyclopropyl-1-(2-fluorophenyl)methanamine
  • N-(4-Fluorobenzyl)-1-(2-fluorophenyl)methanamine
  • N-(3-Fluorobenzyl)-1-(2-fluorophenyl)methanamine
  • (R)-1-Cyclopropyl-1-(2-fluorophenyl)methanamine hydrochloride (1:1)
  • (1-(2-Fluorophenyl)cyclobutyl)methanamine hydrochloride
  • (1-(2-FLUOROPHENYL)CYCLOPROPYL)METHANAMINE HYDROCHLORIDE