1-(2-Fluorophenyl)methanamine

Modify Date: 2024-01-04 08:47:10

1-(2-Fluorophenyl)methanamine Structure
1-(2-Fluorophenyl)methanamine structure
Common Name 1-(2-Fluorophenyl)methanamine
CAS Number 89-99-6 Molecular Weight 125.144
Density 1.1±0.1 g/cm3 Boiling Point 185.9±0.0 °C at 760 mmHg
Molecular Formula C7H8FN Melting Point N/A
MSDS Chinese USA Flash Point 67.2±0.0 °C
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name 2-Fluorobenzylamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 185.9±0.0 °C at 760 mmHg
Molecular Formula C7H8FN
Molecular Weight 125.144
Flash Point 67.2±0.0 °C
Exact Mass 125.064079
PSA 26.02000
LogP 1.14
Vapour Pressure 0.7±0.3 mmHg at 25°C
Index of Refraction 1.523

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H314
Precautionary Statements P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive
Risk Phrases R20/21/22;R34
Safety Phrases S26-S27-S36/37/39-S45
RIDADR UN 2735 8/PG 2
WGK Germany 3
Packaging Group III
Hazard Class 8
HS Code 2921420090

 Synthetic Route

~97%

1-(2-Fluorophenyl)methanamine Structure

1-(2-Fluorophen...

CAS#:89-99-6

Literature: Takamizawa; Wakasa; Fuchikami Synlett, 2001 , # 10 p. 1623 - 1625

~57%

1-(2-Fluorophenyl)methanamine Structure

1-(2-Fluorophen...

CAS#:89-99-6

Literature: Organic Letters, , vol. 4, # 12 p. 2055 - 2058

~%

1-(2-Fluorophenyl)methanamine Structure

1-(2-Fluorophen...

CAS#:89-99-6

Literature: Journal of Medicinal Chemistry, , vol. 49, # 21 p. 6197 - 6208

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1-(2-Fluorophenyl)methanamine Structure

1-(2-Fluorophen...

CAS#:89-99-6

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 15, p. 386 - 387

~%

1-(2-Fluorophenyl)methanamine Structure

1-(2-Fluorophen...

CAS#:89-99-6

Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 15, p. 386 - 387

 Customs

HS Code 2921499090
Summary 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Articles2

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Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).

Bioorg. Med. Chem. Lett. 17 , 2171-2178, (2007)

The design, synthesis, and SAR of a series of substituted spirohydantoins are described. Optimization of an in-house screening hit gave compounds that exhibited potent binding affinity and functional ...

9-(2-Fluorobenzyl)-6-(methylamino)-9H-purine hydrochloride. Synthesis and anticonvulsant activity.

J. Med. Chem. 29(7) , 1133-4, (1986)

 Synonyms

o-Fluorobenzylamine
1-(2-Fluorophenyl)methylamine
MFCD00008107
1-(2-Fluorophenyl)methanamine
Z1R BF
(2-Fluorophenyl)methanamine
Benzenemethanamine, 2-fluoro-
EINECS 201-957-9