Salmeterol

Suppliers

Names

[ Name ]:
Salmeterol

[Synonym ]:
(+-)-4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedi
SAMETEROL
SalmeterolXenofoate
4-Hydroxy-3-[hydroxymethyl]phenyl-N-[6-phenylbutoxyhexyl]ethanolamine
Salmeterol
2-(Hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol
2-(hydroxymethyl)-4-[1-hydroxy-2-({6-[(4-phenylbutyl)oxy]hexyl}amino)ethyl]phenol
2-hydroxymethyl-4-{1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl}phenol
(±)-4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol
MFCD00867037
serevent (R)
(±)-4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-a,a1-diol
1,3-Benzenedimethanol, 4-hydroxy-α-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-
SALMETEROL(SUBJECTTOPATENTFREE)
4-HYDROXY-A1-[[[6-(4-PHENYLBUTOXY)HEXYL]AMINO]METHYL]-1,3-BENZENEDIMETHANOL

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
603.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₇NO₄

[ Molecular Weight ]:
415.566

[ Flash Point ]:
318.5±31.5 °C

[ Exact Mass ]:
415.272247

[ PSA ]:
81.95000

[ LogP ]:
3.07

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.566

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ6457000

CHEMICAL NAME :: 1,3-Benzenedimethanol, 4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)met hyl)-, (+-)-

CAS REGISTRY NUMBER :: 89365-50-4

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C25-H37-N-O4

MOLECULAR WEIGHT :: 415.63

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5600 ug/kg/28D-I

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in spleen Immunological Including Allergic - decreased immune response

REFERENCE :: IJIMDS International Journal of Immunopharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1979- Volume(issue)/page/year: 18,523,1996

Safety Information

[ RTECS ]:
CZ6457000

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Phenylbutan-1-ol
[4-(6-BROMO-HEXYLOXY)-BUTYL]-BENZENE
4-[2-[benzyl-[6-(4-phenylbutoxy)hexyl]amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol
1,6-Dibromohexane
Salicylaldehyde
5-(Bromoacetyl)-2-hydroxybenzaldehyde
6-N-Benzylamino-1-(4'-phenylbutoxy)Hexane
2-hydroxy-5-[[[6,6-(4-phenylbutoxy)hexylbenzyl]amino]acetyl]benzaldehyde
5-bromoacetyl-2-bensyloxybenzoic acid methyl ester

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%