Salmeterol

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Names

[ CAS No. ]:
89365-50-4

[ Name ]:
Salmeterol

[Synonym ]:
(+-)-4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedi
SAMETEROL
SalmeterolXenofoate
4-Hydroxy-3-[hydroxymethyl]phenyl-N-[6-phenylbutoxyhexyl]ethanolamine
Salmeterol
2-(Hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol
2-(hydroxymethyl)-4-[1-hydroxy-2-({6-[(4-phenylbutyl)oxy]hexyl}amino)ethyl]phenol
2-hydroxymethyl-4-{1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl}phenol
(±)-4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol
MFCD00867037
serevent (R)
(±)-4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-a,a1-diol
1,3-Benzenedimethanol, 4-hydroxy-α-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-
SALMETEROL(SUBJECTTOPATENTFREE)
4-HYDROXY-A1-[[[6-(4-PHENYLBUTOXY)HEXYL]AMINO]METHYL]-1,3-BENZENEDIMETHANOL

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
603.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H37NO4

[ Molecular Weight ]:
415.566

[ Flash Point ]:
318.5±31.5 °C

[ Exact Mass ]:
415.272247

[ PSA ]:
81.95000

[ LogP ]:
3.07

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.566

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CZ6457000
CHEMICAL NAME :
1,3-Benzenedimethanol, 4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)met hyl)-, (+-)-
CAS REGISTRY NUMBER :
89365-50-4
LAST UPDATED :
199712
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C25-H37-N-O4
MOLECULAR WEIGHT :
415.63

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
5600 ug/kg/28D-I
TOXIC EFFECTS :
Liver - changes in liver weight Blood - changes in spleen Immunological Including Allergic - decreased immune response
REFERENCE :
IJIMDS International Journal of Immunopharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1979- Volume(issue)/page/year: 18,523,1996

Safety Information

[ RTECS ]:
CZ6457000

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Phenylbutan-1-ol
  • [4-(6-BROMO-HEXYLOXY)-BUTYL]-BENZENE
  • 4-[2-[benzyl-[6-(4-phenylbutoxy)hexyl]amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol
  • 1,6-Dibromohexane
  • Salicylaldehyde
  • 5-(Bromoacetyl)-2-hydroxybenzaldehyde
  • 6-N-Benzylamino-1-(4'-phenylbutoxy)Hexane
  • 2-hydroxy-5-[[[6,6-(4-phenylbutoxy)hexylbenzyl]amino]acetyl]benzaldehyde
  • 5-bromoacetyl-2-bensyloxybenzoic acid methyl ester

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • Salmeterol
  • Salmeterol-d4
  • Salmeterol-D3
  • N-Boc-salmeterol
  • Salmeterol Xinafoate
  • Salmeterol Impurity 5
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • Benzenepropanoic acid, 3-(bromomethyl)-5-cyano-, methyl ester
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide