Salmeterol

Modify Date: 2024-01-02 18:11:45

Salmeterol structure	Common Name	Salmeterol
	CAS Number	89365-50-4	Molecular Weight	415.566
	Density	1.1±0.1 g/cm3	Boiling Point	603.0±55.0 °C at 760 mmHg
	Molecular Formula	C₂₅H₃₇NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	318.5±31.5 °C

Use of Salmeterol

Salmeterol is a long-acting beta2-adrenergic receptor (beta 2AR) agonist used clinically to treat asthma.Target: beta2-Adrenergic ReceptorSalmeterol is a long-acting beta2-adrenergic receptor agonist drug that is prescribed for the treatment of asthma and chronic obstructive pulmonary disease (COPD). salmeterol also binds with very high affinity at a second site, termed the "exosite", and that this exosite contributes to the long duration of action of salmeterol [1].

Name	2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol
Synonym	More Synonyms

Description	Salmeterol is a long-acting beta2-adrenergic receptor (beta 2AR) agonist used clinically to treat asthma.Target: beta2-Adrenergic ReceptorSalmeterol is a long-acting beta2-adrenergic receptor agonist drug that is prescribed for the treatment of asthma and chronic obstructive pulmonary disease (COPD). salmeterol also binds with very high affinity at a second site, termed the "exosite", and that this exosite contributes to the long duration of action of salmeterol [1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Others
References	[1]. Rong, Y., et al., Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol. Biochemistry, 1999. 38(35): p. 11278-86.

Density	1.1±0.1 g/cm3
Boiling Point	603.0±55.0 °C at 760 mmHg
Molecular Formula	C₂₅H₃₇NO₄
Molecular Weight	415.566
Flash Point	318.5±31.5 °C
Exact Mass	415.272247
PSA	81.95000
LogP	3.07
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.566
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CZ6457000

CHEMICAL NAME :: 1,3-Benzenedimethanol, 4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)met hyl)-, (+-)-

CAS REGISTRY NUMBER :: 89365-50-4

LAST UPDATED :: 199712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C25-H37-N-O4

MOLECULAR WEIGHT :: 415.63

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5600 ug/kg/28D-I

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in spleen Immunological Including Allergic - decreased immune response

REFERENCE :: IJIMDS International Journal of Immunopharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1979- Volume(issue)/page/year: 18,523,1996

RTECS	CZ6457000
HS Code	2922509090

Precursor 9
CAS#:3360-41-6 4-Phenylbutan-1-ol CAS#:94749-73-2 [4-(6-BROMO-HEX... CAS#:934842-69-0 4-[2-[benzyl-[6... CAS#:629-03-8 1,6-Dibromohexane
CAS#:90-02-8 Salicylaldehyde CAS#:115787-50-3 5-(Bromoacetyl)... CAS#:97664-55-6 6-N-Benzylamino... CAS#:163923-19-1 2-hydroxy-5-[[[...
CAS#:27475-14-5 5-bromoacetyl-2...
DownStream 0

HS Code	2922509090
Summary	2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

(+-)-4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedi

SAMETEROL

SalmeterolXenofoate

4-Hydroxy-3-[hydroxymethyl]phenyl-N-[6-phenylbutoxyhexyl]ethanolamine

Salmeterol

2-(Hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol

2-(hydroxymethyl)-4-[1-hydroxy-2-({6-[(4-phenylbutyl)oxy]hexyl}amino)ethyl]phenol

2-hydroxymethyl-4-{1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl}phenol

(±)-4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol

MFCD00867037

serevent (R)

(±)-4-Hydroxy-a1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-m-xylene-a,a1-diol

1,3-Benzenedimethanol, 4-hydroxy-α-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-

SALMETEROL(SUBJECTTOPATENTFREE)

4-HYDROXY-A1-[[[6-(4-PHENYLBUTOXY)HEXYL]AMINO]METHYL]-1,3-BENZENEDIMETHANOL

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Salmeterol
Price: ￥2486.0/25mg ￥776.0/5mg ￥4726.0/50mg ￥1226.0/10mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Salmeterol
Price: $350.0/100mg $700.0/250mg $1300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Salmeterol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

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Price: $166/10mM*1mLinDMSO

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Salmeterol

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