IMIRESTAT
Suppliers
Names
[ CAS No. ]:
89391-50-4
[ Name ]:
IMIRESTAT
[Synonym ]:
Imirestatum [INN-Latin]
Alcon 1576
2,7-Difluorospiro(fluorene-9,4'-imidazolidine)-2',5'-dione
2,7-di-fluoro-spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione
Imirestat
spiro-[2,7-difluorofluoren-9,4'-imidazolidine]-2',5'-dione
Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione,2,7-difluoro
[14C]-Imirestat
Spiro-(2,7-difluoro-9H-fluoren-9,4'-imidazolidine)-2',5'-dione
HOE 843
Chemical & Physical Properties
[ Density]:
1.58g/cm3
[ Molecular Formula ]:
C15H8F2N2O2
[ Molecular Weight ]:
286.23300
[ Exact Mass ]:
286.05500
[ PSA ]:
58.20000
[ LogP ]:
2.68580
[ Index of Refraction ]:
1.692
[ Storage condition ]:
2-8℃
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WH1307300
- CHEMICAL NAME :
- Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-
- CAS REGISTRY NUMBER :
- 89391-50-4
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C15-H8-F2-N2-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 700 mg/kg/14D-I
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),137,1997
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 700 mg/kg/14D-I
- TOXIC EFFECTS :
- Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)
- REFERENCE :
- FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 36(1, Pt 2),137,1997