Dimethyloxalylglycine

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Names

[ CAS No. ]:
89464-63-1

[ Name ]:
Dimethyloxalylglycine

[Synonym ]:
Glycine, N-(2-methoxy-1,2-dioxoethyl)-, methyl ester
Dimethyloxalylglycine
methyl 2-[(2-methoxy-2-oxoethyl)amino]-2-oxoacetate
Methyl N-[methoxy(oxo)acetyl]glycinate
DMOG

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Melting Point ]:
46-48ºC

[ Molecular Formula ]:
C6H9NO5

[ Molecular Weight ]:
175.139

[ Exact Mass ]:
175.048065

[ PSA ]:
81.70000

[ LogP ]:
-0.56

[ Appearance of Characters ]:
Solid | white to off-white

[ Index of Refraction ]:
1.440

[ Storage condition ]:
Refrigerator

[ Water Solubility ]:
H2O: >30mg/mL | Soluble in water at 30mg/ml.

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R22

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2924199090

Synthetic Route

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Anti-chondroitin sulfate proteoglycan 4-specific antibodies modify the effects of vemurafenib on melanoma cells differentially in normoxia and hypoxia.

Int. J. Oncol. 47 , 81-90, (2015)

Chondroitin sulfate proteoglycan 4 (CSPG4), a highly immunogenic melanoma tumor antigen, is a potential target for antibody-based immunotherapy. The mechanism by which CSPG4 affects melanoma progressi...

A novel effect of DMOG on cell metabolism: direct inhibition of mitochondrial function precedes HIF target gene expression.

Biochim. Biophys. Acta 1847 , 1254-66, (2015)

Abnormal accumulation of oncometabolite fumarate and succinate is associated with inhibition of mitochondrial function and carcinogenesis. By competing with α-ketoglutarate, oncometabolites also activ...

Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells.

Diabetologia 57(8) , 1635-44, (2014)

Hypoxic damage complicates islet isolation for transplantation and may contribute to beta cell failure in type 2 diabetes. Polymorphisms in the SLC30A8 gene, encoding the secretory granule zinc transp...


More Articles


Related Compounds

  • 1-[(4-bromothiophen-2-yl)methyl]-1H-1,2,3-triazole-4-carboxylic acid
  • 1-(cyclopentylmethyl)-1H-1,2,3-triazole-4-carboxylic acid
  • 2-{[(Tert-butoxy)carbonyl]amino}-2-(2,3-dihydro-1,4-benzodioxin-6-yl)acetic acid
  • 1-(2-Ethoxyethyl)-5-isopropyl-1h-1,2,3-triazole-4-carboxylic acid
  • 4-Amino-2-cyclopropylbutan-2-ol
  • 2-[(2-chlorophenyl)({[(9H-fluoren-9-yl)methoxy]carbonyl})amino]acetic acid
  • 2-(2-Aminopropan-2-yl)pyrimidin-4-amine
  • N-cyclobutyl-2-ethylaniline
  • Benzyl 4-(2-nitrophenyl)piperazine-1-carboxylate
  • 1-(3-aminopropyl)-1H-1,2,3-triazole-4-carboxylic acid
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