9-Aminoacridine

Names

[ CAS No. ]:
90-45-9

[ Name ]:
9-Aminoacridine

[Synonym ]:
MFCD00037839
EINECS 201-995-6
9-Aminoacridine
9-aminoacridiniun

Chemical & Physical Properties

[ Density]:
1.268g/cm3

[ Boiling Point ]:
413.5ºC at 760 mmHg

[ Melting Point ]:
241ºC

[ Molecular Formula ]:
C₁₃H₁₀N₂

[ Molecular Weight ]:
194.23200

[ Flash Point ]:
233.2ºC

[ Exact Mass ]:
194.08400

[ PSA ]:
38.91000

[ LogP ]:
3.55140

[ Index of Refraction ]:
1.78

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
ethanol: hazy

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR7300000

CHEMICAL NAME :: Acridine, 9-amino-

CAS REGISTRY NUMBER :: 90-45-9

BEILSTEIN REFERENCE NO. :: 0141171

LAST UPDATED :: 199710

DATA ITEMS CITED :: 32

MOLECULAR FORMULA :: C13-H10-N2

MOLECULAR WEIGHT :: 194.25

WISWESSER LINE NOTATION :: T C666 BNJ IZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 68 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 10 mmol/L

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 44,53,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - B0081 No. of Facilities: 75 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 299 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
AR7300000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Articles

Genotoxicity testing of esterified propoxylated glycerol (EPG).

Regul Toxicol Pharmacol 70 Suppl 2 , S131-42, (2014)

Four versions of esterified propoxylated glycerols (EPGs) were evaluated for potential genotoxicity using a range of in vitro and in vivo assays. H-EPG-05 HR/SO 9:1, H-EPG-05 soyate, and H-EPG-14 soya...

Mutagenicity and DNA-damaging potential of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid in vitro.

Food Chem. Toxicol. 77 , 82-92, (2015)

The aim of this study was to evaluate in vitro toxicity of clenbuterol and its metabolite 4-amino-3,5-dichlorobenzoic acid. Cytotoxicity and pro-oxidative effect of both compounds were studied on huma...

Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction.

J. Lipid Res. 55(11) , 2354-69, (2014)

Mammalian kidneys are rich in sulfatides. Papillary sulfatides, especially, contribute to renal adaptation to chronic metabolic acidosis. Due to differences in their cer-amide (Cer) anchors, the struc...

9-AMINOACRIDINE HCL
bis-9-aminoacridine
9-Aminoacridine HCl H2O
2-nitro-9-aminoacridine
1-Nitro-9-aminoacridine
3-nitro-9-aminoacridine
1-(3-(3,4-dihydroisoquinolin-2(1H)-yl)azetidin-1-yl)-3-(3-fluoro-4-methylphenyl)propan-1-one hydrochloride
(3-(benzyloxy)phenyl)(3-(3,4-dihydroisoquinolin-2(1H)-yl)azetidin-1-yl)methanone hydrochloride
(3-(3,4-dihydroisoquinolin-2(1H)-yl)azetidin-1-yl)(4-(2-methoxyethoxy)phenyl)methanone hydrochloride
cyclopropyl(3-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)azetidin-1-yl)methanone hydrochloride
1-(3-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)azetidin-1-yl)pentan-1-one hydrochloride
(3-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)azetidin-1-yl)(4-propylphenyl)methanone hydrochloride
(2-chloro-4-fluorophenyl)(3-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)azetidin-1-yl)methanone hydrochloride
1-(3-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)azetidin-1-yl)-3-(4-propoxyphenyl)propan-1-one hydrochloride
1-(3-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)azetidin-1-yl)-3-(4-(trifluoromethyl)phenyl)propan-1-one hydrochloride
3-(1-(Benzofuran-2-carbonyl)azetidin-3-yl)imidazolidine-2,4-dione

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.