Chitosan

Names

[ Name ]:
Chitosan

[Synonym ]:
EINECS 222-311-2
Poly(beta-(1,4)-D-glucosamine)
Poly(beta-(1,4)-2-amino-2-deoxy-D-glucose)
MFCD00161512
Chitosan

Chemical & Physical Properties

[ Density]:
1.75g/cm3

[ Melting Point ]:
88ºC

[ Molecular Formula ]:
(C₆H₁₃NO₅)n

[ Molecular Weight ]:
161.16 (monomer)

[ Index of Refraction ]:
1.7

[ Storage condition ]:
room temp

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
dilute aqueous acid (pH <6.5).: soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FM6300000

CHEMICAL NAME :: Chitosan

CAS REGISTRY NUMBER :: 9012-76-4

LAST UPDATED :: 199701

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 957 gm/kg/58D-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

REFERENCE :: BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 15,555,1976

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22-36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
-

[ RTECS ]:
FM6300000

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Chitosan oligosaccharides prevented retinal ischemia and reperfusion injury via reduced oxidative stress and inflammation in rats.

Exp. Eye Res. 130 , 38-50, (2015)

The purpose of the present study was to investigate the protective effect and mechanism of chitosan oligonucleotides (COS) on retinal ischemia and reperfusion (I/R) injury. Rats pretreated with PBS, l...

Cell–scaffold interaction within engineered tissue

Exp. Cell Res. 323(2) , 346-51, (2014)

The structure of a tissue engineering scaffold plays an important role in modulating tissue growth. A novel gelatin–chitosan (Gel–Cs) scaffold with a unique structure produced by three-dimensional pri...

Structural insights into the substrate-binding mechanism for a novel chitosanase.

Biochem. J. 461(2) , 335-45, (2014)

Chitosanase is able to specifically cleave β-1,4-glycosidic bond linkages in chitosan to produce a chito-oligomer product, which has found a variety of applications in many areas, including functional...