9-Aminocamptothecin

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Names

[ CAS No. ]:
91421-43-1

[ Name ]:
9-Aminocamptothecin

[Synonym ]:
(4S)-10-Amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
MFCD00909855
Camptothecin,9-amino
9-Amino-20-camptothecin
9-Amino-camptothecin
1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-amino-4-ethyl-4-hydroxy-, (4S)-
9-AC
9-AMINO-20(S)-CAMPTOTHECIN
(20S)-9-aminocamptothecin
(S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
819.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H17N3O4

[ Molecular Weight ]:
363.367

[ Flash Point ]:
449.5±34.3 °C

[ Exact Mass ]:
363.121918

[ PSA ]:
107.44000

[ LogP ]:
0.44

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.771

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T+

[ RIDADR ]:
2811.0

[ Hazard Class ]:
6.1

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • rubitecan
  • 9-nitro-10-(p-toluenesulfonyl)camptothecin
  • (S)-4-ethyl-4-hydroxy-10-nitro-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl benzenesulfonate
  • Campathecin
  • (S)-10-Hydroxycamptothecin
  • 9-Nitro-10-hydroxy camptothecin
  • 2,6-Dinitrobenzaldehyde
  • 2-amino-6-nitrobenzaldehyde ethylene acetal

DownStream

  • 9-Hydroxycamptothecin
  • Campathecin
  • 9-Methoxycamptothecine

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 9-aminocamptothecin sodium salt
  • 9-amino-20-camptothecin
  • 9-(2-prop-1-enoxyethyl)carbazole
  • 9-chloro-5-methoxy-3-nitroacridine
  • 9-phenylnon-8-enal
  • 9-methyl-4-(1-methylindol-2-yl)carbazole
  • 3-(3,4-dichlorophenyl)-5-(3-pyridin-3-ylphenyl)-2-(trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidin-7-one
  • Methyl 3-acetamidobicyclo[1.1.1]pentane-1-carboxylate
  • tert-Butyl 2-(4-fluorophenyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate
  • 2-Isopropoxy-4-(3,4,5-trimethylpiperazin-1-yl)aniline
  • 3-(Chloromethyl)-3-(methoxymethyl)-2-methyloxolane
  • 3-(Chloromethyl)-2-methyl-3-propyloxolane
  • 3-(Chloromethyl)-3-(2-methoxyethyl)-2-methyloxolane
  • 3-(Chloromethyl)-2-methyl-3-(propan-2-yl)oxolane
  • 3-(Butan-2-yl)-3-(chloromethyl)-2-methyloxolane
  • 3-(Bromomethyl)-2-methyl-3-(2-methylpropyl)oxolane
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