3-(tert-butyldimethylsilyloxy)glutaric anhydride

Suppliers

Names

[ Name ]:
3-(tert-butyldimethylsilyloxy)glutaric anhydride

[Synonym ]:
4-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}dihydro-2H-pyran-2,6(3H)-dione
2H-Pyran-2,6(3H)-dione, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]dihydro-
MFCD00075235
4-[tert-butyl(dimethyl)silyl]oxyoxane-2,6-dione
4-{[tert-Butyl(dimethyl)silyl]oxy}dihydro-2H-pyran-2,6(3H)-dione

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
302.4±35.0 °C at 760 mmHg

[ Melting Point ]:
79-81 °C(lit.)

[ Molecular Formula ]:
C₁₁H₂₀O₄Si

[ Molecular Weight ]:
244.360

[ Flash Point ]:
113.6±21.5 °C

[ Exact Mass ]:
244.113083

[ PSA ]:
52.60000

[ LogP ]:
1.55

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.452

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2931900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]pentanedioic Acid Diethyl Ester
Diethyl 3-hydroxypentanedioate
tert-Butyldimethylsilyl chloride

DownStream

3-[[(1,1-dimethyl)dimethylsily]oxy]pentanedioic acid monomethyl ester
Mevastatin
(3R)-3-(tert-Butyldimethylsilyl)oxypentanedioate-1-methyl monoester
5-Oxorosuvastatin Methyl Ester
Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate
(s)-3-[[(1,1-dimethyl)dimethylsily]oxy]pentanedioic acid monomethyl ester

Customs

[ HS Code ]: 2931900090

[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Articles

A modular approach to the synthesis of new reagents useful in the chemical synthesis of modified DNA probes: derivatives of 3-(tert-butyldimethylsiloxy)glutaric anhydride as versatile building blocks in the synthesis of new phosphoramidites and modified solid supports.

Bioconjug. Chem. 15(3) , 583-93, (2004)

We present a flexible and cost-efficient synthetic strategy for the preparation of a new family of phosphoramidite and solid-support reagents that can introduce a broad range of modifications into DNA...

3-(tert-Butyldimethylsilyloxy)glutaric Acid
(3R)-3-(tert-Butyldimethylsilyloxy)glutaric acid-1-((R)-(-)-mandelic acid ester
3-(tert-butyldimethylsilyloxy)phenyl acetate
3-tert-butyldimethylsilyloxy-3',4,4',5'-tetramethyloxystilbene
3-(tert-butyldimethylsilyloxy)-5-methoxybenzyl alcohol
3-((TERT-BUTYLDIMETHYLSILYLOXY)METHYL)-5-PHENYLPYRIDINE
5-(2,6-Dichlorophenyl)-1,3-oxazole-4-carboxylic acid
[(2,3-Dimethylphenyl)methyl](2-methylbutan-2-yl)amine
2-{[(2,3-Dimethylphenyl)methyl]amino}-2-methylpropan-1-ol
1-(4-Methylcyclohexyl)azetidin-3-ol
3-[3-(trifluoromethyl)-1H-pyrazol-1-yl]benzoic acid
1-Bromo-2-methanesulfonyl-2-methylpropane
5-(4-Chloro-2-fluorophenyl)-1,3-oxazole-4-carboxylic acid
5-(3-Methoxy-4-methyl-phenyl)-oxazole-4-carboxylic acid
1-[(3-methoxyphenyl)methyl]-1H-pyrazole
5-bromo-8-(1-methyl-1H-pyrazol-4-yl)isoquinoline

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.