3-(tert-butyldimethylsilyloxy)glutaric anhydride

3-(tert-butyldimethylsilyloxy)glutaric anhydride Structure
3-(tert-butyldimethylsilyloxy)glutaric anhydride structure
Common Name 3-(tert-butyldimethylsilyloxy)glutaric anhydride
CAS Number 91424-40-7 Molecular Weight 244.360
Density 1.0±0.1 g/cm3 Boiling Point 302.4±35.0 °C at 760 mmHg
Molecular Formula C11H20O4Si Melting Point 79-81 °C(lit.)
MSDS Chinese USA Flash Point 113.6±21.5 °C
Symbol GHS07
GHS07
Signal Word Warning

A modular approach to the synthesis of new reagents useful in the chemical synthesis of modified DNA probes: derivatives of 3-(tert-butyldimethylsiloxy)glutaric anhydride as versatile building blocks in the synthesis of new phosphoramidites and modified solid supports.

Bioconjug. Chem. 15(3) , 583-93, (2004)

We present a flexible and cost-efficient synthetic strategy for the preparation of a new family of phosphoramidite and solid-support reagents that can introduce a broad range of modifications into DNA probes. The key intermediate material 3 is synthesized usi...