DL-γ-Amino-β-hydroxybutyric acid

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Names

[ CAS No. ]:
924-49-2

[ Name ]:
DL-γ-Amino-β-hydroxybutyric acid

[Synonym ]:
3-Hydroxy-4-aminobutyric acid
γ-amino-β-hydroxybutyric acid
3-hydroxy-4-amino-butyric acid (GABOB)
3-hydroxy-GABA
β-Hydroxy-GABA
3-hydroxy-4-amino-butyric acid
Butanoic acid, 4-amino-3-hydroxy-
β-Hydroxy-γ-aminobutyric acid
4-Amino-3-hydroxybutanoic acid
g-Amino-b-hydroxybutyric Acid
EINECS 213-106-9
DL-4-Amino-3-hydroxybutanoic acid
DL-γ-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE
DL-4-Amino-3-hydroxybutyric acid
MFCD00008141
(±)-4-Amino-3-hydroxybutyric acid
γ-Amino-β-hydroxy-n-butyric acid
UNII:1ZHM019FLD
z-gabob-oh

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
374.5±32.0 °C at 760 mmHg

[ Melting Point ]:
223ºC (dec.)(lit.)

[ Molecular Formula ]:
C4H9NO3

[ Molecular Weight ]:
119.119

[ Flash Point ]:
180.3±25.1 °C

[ Exact Mass ]:
119.058243

[ PSA ]:
83.55000

[ LogP ]:
-1.73

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.511

[ Water Solubility ]:
almost transparency

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
ES7015000

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (+/-)-maleic acid allyl ester-(2,3-epoxy-propyl ester)
  • 4-Aminobutanoic acid
  • N-(3-cyano-2-hydroxy-propyl)benzamide
  • (Z)-4-phthalimidocrotonic acid
  • methyl 4-(acetylamino)-3-hydroxybutanoate

DownStream

  • DL-Carnitine
  • Glycine
  • 4-trimethylsilyloxypyrrolidin-2-one
  • (R)-(+)-4-Hydroxy-2-pyrrolidinone
  • TACA
  • 4-(dimethylamino)-3-hydroxybutanoic acid
  • tert-Butyl 4-hydroxy-2-oxopyrrolidine-1-carboxylate

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA(C) receptors.

Bioorg. Med. Chem. Lett. 18 , 402-4, (2008)

The R- and S-enantiomers of 4-amino-3-hydroxybutanoic acid (GABOB) were full agonists at human recombinant rho1 GABA(C) receptors. Their enantioselectivity (R>S) matched that reported for their agonis...

GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.

J. Med. Chem. 28(11) , 1612-7, (1985)

(RS)-5-(Aminomethyl)-2-isoxazolin-3-ol (dihydromuscimol, DHM) is a potent 4-aminobutyric acid (GABA) agonist, the inhibitory effects of which on neurons are sensitive to the antagonist bicuculline met...

Formation of gamma-amino-beta-hydroxybutyric acid from 2-hydroxyputrescine in rat brain.

J. Neurochem. 51(2) , 548-51, (1988)

gamma-Amino-beta-[3H]hydroxybutyric acid ([3H]-GABOB) was formed in rat brain from 2-[3H]-hydroxyputrescine that had been chemically synthesized from 2-oxoputrescine and [3H]sodium borohydride. After ...


More Articles

Related Compounds

  • DL-γ-Amino-β-hydroxybutyric acid
  • DL-γ-Amino-β-hydroxybutyric acid
  • DL-Threonine
  • z-4-amino-3-hydroxybutyric acid
  • (S)-(+)-4-Amino-3-hydroxybutyric acid
  • 2-Amino-3-hydroxybutanoic acid
  • 2-(1H-pyrazol-4-yl)benzene-1,4-diol
  • 2-{1-[(5-Methyl-1,2-oxazol-4-yl)methyl]piperidin-4-yl}-6-(pyridin-4-yl)-1,8-naphthyridine
  • 1-[(1-Amino-4-methylcyclohexyl)methyl]-3-ethylurea
  • [1-(Adamantan-2-yl)ethyl](pentan-3-yl)amine
  • 2-(4-fluorophenyl)-5-{[3-(trifluoromethyl)phenyl]methyl}-4H,5H-pyrazolo[1,5-a]pyrazin-4-one
  • 4-(Cyclopropylmethyl)-8,11-dithia-4,6-diazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-3-one
  • 1-methyl-4-(morpholin-2-yl)-1H-indole
  • 5-hexyl-2-(3-methoxyphenyl)-4H,5H-pyrazolo[1,5-a]pyrazin-4-one
  • 4-{5-[(2-Fluorophenyl)methyl]-octahydropyrrolo[3,4-c]pyrrol-2-yl}-6-methylpyrimidine
  • 2-(Cyclopentylsulfanyl)-1-[5-(6-methylpyrimidin-4-yl)-octahydropyrrolo[3,4-c]pyrrol-2-yl]ethan-1-one