DL-γ-Amino-β-hydroxybutyric acid

Modify Date: 2024-01-09 12:00:32

DL-γ-Amino-β-hydroxybutyric acid Structure
DL-γ-Amino-β-hydroxybutyric acid structure
Common Name DL-γ-Amino-β-hydroxybutyric acid
CAS Number 924-49-2 Molecular Weight 119.119
Density 1.3±0.1 g/cm3 Boiling Point 374.5±32.0 °C at 760 mmHg
Molecular Formula C4H9NO3 Melting Point 223ºC (dec.)(lit.)
MSDS Chinese USA Flash Point 180.3±25.1 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of DL-γ-Amino-β-hydroxybutyric acid


Gamibetal is the gamma-amino-beta-hydroxybutyric acid. Gamibetal has the potential for the research of epilepsy[1].

 Names

Name 4-Amino-3-hydroxybutyric Acid
Synonym More Synonyms

 DL-γ-Amino-β-hydroxybutyric acid Biological Activity

Description Gamibetal is the gamma-amino-beta-hydroxybutyric acid. Gamibetal has the potential for the research of epilepsy[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Grbesa B, et al. Gamibetal (gama-amino-beta-hidroksibuterna kiselina--GABOB) u lecenju epilepsije [Gamibetal (gamma-amino-beta-hydroxybutyric acid--GABOB) in the treatment of epilepsy]. Med Glas. 1967;21(3):75-77.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 374.5±32.0 °C at 760 mmHg
Melting Point 223ºC (dec.)(lit.)
Molecular Formula C4H9NO3
Molecular Weight 119.119
Flash Point 180.3±25.1 °C
Exact Mass 119.058243
PSA 83.55000
LogP -1.73
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.511
Water Solubility almost transparency

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS ES7015000
HS Code 2922509090

 Synthetic Route

~72%

DL-γ-Amino-β-hydroxybutyric acid Structure

DL-γ-Amino-β-hy...

CAS#:924-49-2

Literature: Mete; Maras; Secen Russian Chemical Bulletin, 2003 , vol. 52, # 8 p. 1879 - 1881

~4%

DL-γ-Amino-β-hydroxybutyric acid Structure

DL-γ-Amino-β-hy...

CAS#:924-49-2

Detail
Literature: Chemistry Letters, , p. 441 - 444

~%

DL-γ-Amino-β-hydroxybutyric acid Structure

DL-γ-Amino-β-hy...

CAS#:924-49-2

Literature: Journal of Organic Chemistry, , vol. 22, p. 228

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DL-γ-Amino-β-hydroxybutyric acid Structure

DL-γ-Amino-β-hy...

CAS#:924-49-2

Literature: Journal of Organic Chemistry, , vol. 19, p. 1589,1591

~%

DL-γ-Amino-β-hydroxybutyric acid Structure

DL-γ-Amino-β-hy...

CAS#:924-49-2

Literature: Liebigs Annalen der Chemie, , p. 985 - 990

~3%

DL-γ-Amino-β-hydroxybutyric acid Structure

DL-γ-Amino-β-hy...

CAS#:924-49-2

Detail
Literature: Chemistry Letters, , p. 441 - 444

 Customs

HS Code 2922509090
Summary 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles25

More Articles
Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA(C) receptors.

Bioorg. Med. Chem. Lett. 18 , 402-4, (2008)

The R- and S-enantiomers of 4-amino-3-hydroxybutanoic acid (GABOB) were full agonists at human recombinant rho1 GABA(C) receptors. Their enantioselectivity (R>S) matched that reported for their agonis...

GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol.

J. Med. Chem. 28(11) , 1612-7, (1985)

(RS)-5-(Aminomethyl)-2-isoxazolin-3-ol (dihydromuscimol, DHM) is a potent 4-aminobutyric acid (GABA) agonist, the inhibitory effects of which on neurons are sensitive to the antagonist bicuculline met...

Formation of gamma-amino-beta-hydroxybutyric acid from 2-hydroxyputrescine in rat brain.

J. Neurochem. 51(2) , 548-51, (1988)

gamma-Amino-beta-[3H]hydroxybutyric acid ([3H]-GABOB) was formed in rat brain from 2-[3H]-hydroxyputrescine that had been chemically synthesized from 2-oxoputrescine and [3H]sodium borohydride. After ...

 Synonyms

3-Hydroxy-4-aminobutyric acid
γ-amino-β-hydroxybutyric acid
3-hydroxy-4-amino-butyric acid (GABOB)
3-hydroxy-GABA
β-Hydroxy-GABA
3-hydroxy-4-amino-butyric acid
Butanoic acid, 4-amino-3-hydroxy-
β-Hydroxy-γ-aminobutyric acid
4-Amino-3-hydroxybutanoic acid
g-Amino-b-hydroxybutyric Acid
EINECS 213-106-9
DL-4-Amino-3-hydroxybutanoic acid
DL-γ-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE
DL-4-Amino-3-hydroxybutyric acid
MFCD00008141
(±)-4-Amino-3-hydroxybutyric acid
γ-Amino-β-hydroxy-n-butyric acid
UNII:1ZHM019FLD
z-gabob-oh
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