Skimmin

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Names

[ CAS No. ]:
93-39-0

[ Name ]:
Skimmin

[Synonym ]:
2H-1-Benzopyran-2-one, 7- (β-D-glucopyranosyloxy)-
7-(Glucosyloxy)coumarin
Skimmin
7-Hydroxycoumarin-7-glucoside
Skimmine
UMBELLIFERONE GLUCOSIDE
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-
Coumarin, 7-(β-D-glucopyranosyloxy)-
2-Oxo-2H-chromen-7-yl β-D-glucopyranoside
HYDROXYCOUMARIN-GLUCOSIDE,7
Skimmin (8CI)
7-(b-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
632.0±55.0 °C at 760 mmHg

[ Melting Point ]:
221-222ºC

[ Molecular Formula ]:
C15H16O8

[ Molecular Weight ]:
324.28

[ Flash Point ]:
239.3±25.0 °C

[ Exact Mass ]:
324.084503

[ PSA ]:
129.59000

[ LogP ]:
-1.50

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.661

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 7-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]-2H-1-benzopyran-2-one
  • Uridine diphosphate glucose
  • 7-Hydroxycoumarine

DownStream

  • 7-Hydroxycoumarine
  • D-glucopyranose

Articles

Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition.

Evid. Based. Complement. Alternat. Med. 2013 , 819296, (2013)

Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent. In the current st...

Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats.

Eur. J. Pharmacol. 692(1-3) , 78-83, (2012)

Skimmin, a major active ingredient from Hydrangea paniculata, was considered to have the possible preventive effect on the progression of diabetic nephropathy based on the traditional Chinese medicine...


More Articles

Related Compounds

  • Skimmin
  • N-propyl-1-(thiophen-2-yl)cyclopentanecarboxamide
  • N-(2-(dimethylamino)-2-(thiophen-3-yl)ethyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
  • (3S)-6-Oxopiperidine-3-carboxylic acid
  • 3-[5-chloro-2-(dimethylamino)-1-(4-methylphenyl)-1H-imidazol-4-yl]-2-cyano-N-(1-phenylethyl)prop-2-enamide
  • (3-Morpholin-4-yltetrahydrothien-3-yl)methylamine hydrochloride
  • 1-amino-N-ethylcyclohexane-1-carboxamide hydrochloride
  • 2-Amino-4-(methylsulfonyl)butanamide hydrobromide
  • N-[3-(Diethylamino)propyl]thiolan-3-amine
  • [(1-Ethylpyrrolidin-2-YL)methyl](2-methylpropyl)amine
  • [(1-Ethylpyrrolidin-2-YL)methyl](thiophen-3-ylmethyl)amine
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