Skimmin

Modify Date: 2024-01-04 14:14:15

Skimmin Structure
Skimmin structure
Common Name Skimmin
CAS Number 93-39-0 Molecular Weight 324.28
Density 1.6±0.1 g/cm3 Boiling Point 632.0±55.0 °C at 760 mmHg
Molecular Formula C15H16O8 Melting Point 221-222ºC
MSDS Chinese USA Flash Point 239.3±25.0 °C

 Use of Skimmin


Skimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity[1].

 Names

Name 7-hydroxycoumarin glucoside
Synonym More Synonyms

 Skimmin Biological Activity

Description Skimmin (Umbelliferone glucoside) is a coumarin found in Hydrangea paniculata, inhibits immune complex deposition, with anti-inflammatory activity[1].
Related Catalog
References

[1]. Zhang S, et al. Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition. Evid Based Complement Alternat Med. 2013;2013:819296.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 632.0±55.0 °C at 760 mmHg
Melting Point 221-222ºC
Molecular Formula C15H16O8
Molecular Weight 324.28
Flash Point 239.3±25.0 °C
Exact Mass 324.084503
PSA 129.59000
LogP -1.50
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.661

 Safety Information

Hazard Codes Xi
RIDADR NONH for all modes of transport

 Synthetic Route

~87%

Skimmin Structure

Skimmin

CAS#:93-39-0

Literature: Bjerre, Jeannette; Nielsen, Erik Holm; Bols, Mikael European Journal of Organic Chemistry, 2008 , # 4 p. 745 - 752

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Skimmin Structure

Skimmin

CAS#:93-39-0

Literature: Phytochemistry (Elsevier), , vol. 28, # 8 p. 2071 - 2078

 Articles2

More Articles
Skimmin, a Coumarin from Hydrangea paniculata, Slows down the Progression of Membranous Glomerulonephritis by Anti-Inflammatory Effects and Inhibiting Immune Complex Deposition.

Evid. Based. Complement. Alternat. Med. 2013 , 819296, (2013)

Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent. In the current st...

Skimmin, a coumarin, suppresses the streptozotocin-induced diabetic nephropathy in wistar rats.

Eur. J. Pharmacol. 692(1-3) , 78-83, (2012)

Skimmin, a major active ingredient from Hydrangea paniculata, was considered to have the possible preventive effect on the progression of diabetic nephropathy based on the traditional Chinese medicine...

 Synonyms

2H-1-Benzopyran-2-one, 7- (β-D-glucopyranosyloxy)-
7-(Glucosyloxy)coumarin
Skimmin
7-Hydroxycoumarin-7-glucoside
Skimmine
UMBELLIFERONE GLUCOSIDE
2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-
Coumarin, 7-(β-D-glucopyranosyloxy)-
2-Oxo-2H-chromen-7-yl β-D-glucopyranoside
HYDROXYCOUMARIN-GLUCOSIDE,7
Skimmin (8CI)
7-(b-D-Glucopyranosyloxy)-2H-1-benzopyran-2-one
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