Anandamide

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Names

[ CAS No. ]:
94421-68-8

[ Name ]:
Anandamide

[Synonym ]:
arachidonic acid ethanolamide
MFCD00153766
(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)-5,8,11,14-icosatetraenamide
N-arachidonoylethanolamide
5,8,11,14-Eicosatetraenamide, N-(2-hydroxyethyl)-, (5Z,8Z,11Z,14Z)-
N-arachidonoylethanolamine
arachidonylethanolamide
5,8,11,14-Eicosatetraenoylethanolamide
N-Arachidonoyl-2-hydroxyethylamide
N-arachidonoyl ethanolamine
arachidonoylethanolamide
Arachidonoyl-EA
(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
522.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H37NO2

[ Molecular Weight ]:
347.535

[ Flash Point ]:
269.7±30.1 °C

[ Exact Mass ]:
347.282440

[ PSA ]:
49.33000

[ LogP ]:
5.66

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.504

[ Storage condition ]:
−20°C

[ Water Solubility ]:
ethanol: soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JX3842500
CHEMICAL NAME :
5,8,11,14-Eicosatetraenamide, N-(2-hydroxyethyl)-, (all-Z)-
CAS REGISTRY NUMBER :
94421-68-8
LAST UPDATED :
199806
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H37-N-O2
MOLECULAR WEIGHT :
347.60

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
140 ug/kg
SEX/DURATION :
female 15-21 day(s) after conception
TOXIC EFFECTS :
Reproductive - Maternal Effects - parturition Reproductive - Maternal Effects - other effects Reproductive - Effects on Newborn - stillbirth
REFERENCE :
NLETDU Neuroendocrinology Letters. (Brain Research Promotion, D-7400, Tubingen, Germany) V.1- 1979- Volume(issue)/page/year: 17,271,1995
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
100 mg/kg
SEX/DURATION :
female 14-18 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - behavioral Reproductive - Effects on Newborn - other postnatal measures or effects
REFERENCE :
PSYCDE Psychoneuroendocrinology. (Elsevier Science, 660 White Plains Road Tarrytown, NY 10591) V.1- 1975- Volume(issue)/page/year: 21,157,1996

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
F: Flammable;

[ Risk Phrases ]:
R11

[ Safety Phrases ]:
24/25-16-7

[ RIDADR ]:
UN 1170 3

[ WGK Germany ]:
3

[ RTECS ]:
JX3842500

[ HS Code ]:
2924199090

Synthetic Route

Precursor & DownStream

Precursor

  • Arachidonic acid
  • 2-Aminoethanol
  • Methyl (5Z,8Z,11Z,14Z)-5,8,11,14-icosatetraenoate
  • Isobutyl chloroformate
  • Arachidonoyl Chloride (Arachidonic Acid Chloride)
  • arachidonic acid imidazolide
  • β-Aminoethanol hydrochloride

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Anandamide (AEA) is an endocannabinoid (EC) that modulates multiple functions in the CNS and that is released in areas of injury, exerting putative neuroprotective actions. In the present study, we ha...


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Related Compounds

  • Anandamide-d4
  • Anandamide-d11
  • anandamide phosphate
  • anandamide [arachidonyl-5,6,8,9,11,12,14,15-3h]
  • 2-(1-Amino-2-methylpropan-2-yl)-5-bromophenol
  • 2,7-dibromo-9-(tetrahydro-2H-pyran-4-yl)-9H-carbazole
  • 3-Hydroxy-3-(4-methanesulfonylphenyl)propanoic acid
  • O-[2-(3-bromo-4-methoxyphenyl)ethyl]hydroxylamine
  • 2-(3-Bromo-5-fluorophenyl)-2-methylpropan-1-amine
  • 2-(2-Bromo-5-fluorophenyl)-2-methylpropan-1-amine
  • 1-(2-Bromo-5-fluorophenyl)-2-methylpropan-1-amine
  • 1-(4-Bromothiophen-2-yl)-2,2-dimethylcyclopropan-1-amine
  • 2-(3,5-Dichlorophenyl)-3-methylbutanoic acid
  • 1-(5-Bromo-2-chlorophenyl)propan-2-one
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