Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate

Suppliers

Names

[ Name ]:
Ethyl 2,6-dichloro-5-fluoro-pyridine-3-acetoacetate

[Synonym ]:
3-Pyridinebutanoic acid, 2,6-dichloro-5-fluoro-β-oxo-, ethyl ester
MFCD00799535
Ethyl 4-(2,6-dichloro-5-fluoro-3-pyridinyl)-3-oxobutanoate
Ethyl 4-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxobutanoate
ethyl 3-(2,6-dichloro-5-fluoropyridin-3-yl)-3-oxopropanoate

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
363.4±37.0 °C at 760 mmHg

[ Melting Point ]:
68-72 °C(lit.)

[ Molecular Formula ]:
C₁₁H₁₀Cl₂FNO₃

[ Molecular Weight ]:
294.106

[ Flash Point ]:
173.6±26.5 °C

[ Exact Mass ]:
293.002167

[ PSA ]:
56.26000

[ LogP ]:
2.41

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.521

[ Storage condition ]:
-20°C Freezer

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

diethyl (2,6-dichloro-5-fluoro-pyridine-3-carbonyl)-malonate
Potassium monoethyl malonate
2,6-Dichloro-5-fluoronicotinonitrile
Monoethyl malonic acid
2,6-dichloro-5-fluoronicotinoyl chloride
2,6-Dihydroxy-5-fluoro-3-cyanopyridine
2,6-Dichloro-5-fluoronicotinic acid
ethyl 2-hydrazono-2-(2,6-dichloro-5-fluoronicotinoyl)acetate
ethyl 2-diazo-2-(2,6-dichloro-5-fluoronicotinoyl)acetate
ethyl 2,6-dichloro-5-fluoropyridine-3-carboxylate

DownStream

ethyl 6-fluoro-1-(4-fluorophenyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
Tosufloxacin pharmaceutical intermediate
Ethyl 7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 6-fluoro-1-(4-fluorophenyl)-7-(3-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 1-(2,4-difluorophenyl)-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,8-naphthyridine-3-carboxylate
ethyl 7-chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,8-naphthyridine-3-carboxylate
Ethyl-2-(2,6-dichlor-5-fluorpyridin-3-carbonyl)-3-(2,4-difluorphenylamino)-acrylat
ethyl 6-fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylate
ethyl 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-yl-1,8-naphthyridine-3-carboxylate

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

2-{[(4-Ethylphenyl)methyl]amino}acetamide
2-(3-Amino-5-fluoropyridin-2-yl)acetic acid
N-(2-(dimethylamino)ethyl)-2-(3-((4-fluorophenyl)sulfonyl)-1H-indol-1-yl)acetamide
2-(2-Chloro-5-fluoropyridin-3-yl)acetic acid
2-(3-((4-fluorophenyl)sulfonyl)-1H-indol-1-yl)-N-(furan-2-ylmethyl)acetamide
2-(4-methyl-2-oxo-1H-pyridin-3-yl)acetonitrile
2-Amino-6-bromo-3-propylquinoline
3-(4-Fluoro-3-nitrophenyl)azetidine
2-(3-((4-fluorophenyl)sulfonyl)-1H-indol-1-yl)-N-(thiophen-2-ylmethyl)acetamide
5-(Azetidin-3-yl)-3-methoxybenzene-1,2-diol

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.