BML-266
Suppliers
Names
[ CAS No. ]:
96969-83-4
[ Name ]:
BML-266
[Synonym ]:
1,4-Bis{[2-(4-hydroxyphenyl)ethyl]amino}-9,10-anthraquinone
9,10-Anthracenedione, 1,4-bis[[2-(4-hydroxyphenyl)ethyl]amino]-
1,4-bis{[2-(4-hydroxyphenyl)ethyl]amino}anthracene-9,10-dione
1,4-bis[(p-hydroxyphenethyl)amino]-anthraquinone
hms3261l04
1,4-di[(4-hydroxyphenethyl)amino]-9,10-dihydroanthracene-9,10-dione
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
780.2±60.0 °C at 760 mmHg
[ Molecular Formula ]:
C30H26N2O4
[ Molecular Weight ]:
478.538
[ Flash Point ]:
425.7±32.9 °C
[ Exact Mass ]:
478.189270
[ PSA ]:
98.66000
[ LogP ]:
4.45
[ Vapour Pressure ]:
0.0±2.8 mmHg at 25°C
[ Index of Refraction ]:
1.733
[ Storage condition ]:
-20°C
MSDS
Safety Information
[ Symbol ]:
GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H400
[ Precautionary Statements ]:
P273
[ Personal Protective Equipment ]:
Eyeshields;Gloves
[ Hazard Codes ]:
N: Dangerous for the environment;
[ Risk Phrases ]:
50/53
[ Safety Phrases ]:
60-61
[ RIDADR ]:
UN 3077 9/PG 3
Articles
J. Med. Chem. 47 , 6292-6298, (2004)
Type 2 human sirtuin (SIRT2) is a NAD(+)-dependent cytoplasmic protein that is colocalized with HDAC6 on microtubules. SIRT2 has been shown to deacetylate alpha-tubulin and to control mitotic exit in ...
J. Med. Chem. 49 , 7239-7241, (2006)
A successful virtual screening experiment of novel SIRT2 inhibitors is described. Four out of 11 experimentally tested compounds showed in vitro inhibitory activity toward SIRT2 in a micromolar level,...