BML-266
Modify Date: 2024-01-27 20:02:15
BML-266 structure
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Common Name | BML-266 | ||
|---|---|---|---|---|
| CAS Number | 96969-83-4 | Molecular Weight | 478.538 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 780.2±60.0 °C at 760 mmHg | |
| Molecular Formula | C30H26N2O4 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 425.7±32.9 °C | |
| Symbol |
GHS09 |
Signal Word | Warning | |
Use of BML-266JFD00244 is a sirtuin 2 (SIRT2) inhibitor. Anti-tumor effect[1]. |
| Name | 1,4-bis[2-(4-hydroxyphenyl)ethylamino]anthracene-9,10-dione |
|---|---|
| Synonym | More Synonyms |
| Description | JFD00244 is a sirtuin 2 (SIRT2) inhibitor. Anti-tumor effect[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 780.2±60.0 °C at 760 mmHg |
| Molecular Formula | C30H26N2O4 |
| Molecular Weight | 478.538 |
| Flash Point | 425.7±32.9 °C |
| Exact Mass | 478.189270 |
| PSA | 98.66000 |
| LogP | 4.45 |
| Vapour Pressure | 0.0±2.8 mmHg at 25°C |
| Index of Refraction | 1.733 |
| Storage condition | -20°C |
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An in silico approach to discovering novel inhibitors of human sirtuin type 2.
J. Med. Chem. 47 , 6292-6298, (2004) Type 2 human sirtuin (SIRT2) is a NAD(+)-dependent cytoplasmic protein that is colocalized with HDAC6 on microtubules. SIRT2 has been shown to deacetylate alpha-tubulin and to control mitotic exit in ... |
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Discovering inhibitors of human sirtuin type 2: novel structural scaffolds.
J. Med. Chem. 49 , 7239-7241, (2006) A successful virtual screening experiment of novel SIRT2 inhibitors is described. Four out of 11 experimentally tested compounds showed in vitro inhibitory activity toward SIRT2 in a micromolar level,... |
| 1,4-Bis{[2-(4-hydroxyphenyl)ethyl]amino}-9,10-anthraquinone |
| 9,10-Anthracenedione, 1,4-bis[[2-(4-hydroxyphenyl)ethyl]amino]- |
| 1,4-bis{[2-(4-hydroxyphenyl)ethyl]amino}anthracene-9,10-dione |
| 1,4-bis[(p-hydroxyphenethyl)amino]-anthraquinone |
| hms3261l04 |
| 1,4-di[(4-hydroxyphenethyl)amino]-9,10-dihydroanthracene-9,10-dione |