Ditolylguanidine
Suppliers
Names
[ CAS No. ]:
97-39-2
[ Name ]:
Ditolylguanidine
[Synonym ]:
MFCD00008513
1,3-Bis(o-tolyl)guanidine
Guanidine, N,N''-bis(2-methylphenyl)-
N,N'-Di-o-tolylguanidine
EINECS 202-577-6
N,N'-Bis(2-methylphenyl)guanidine
Di-o-tolylguanidine
Guanidine, 1,3-di-o-tolyl-
1R BMYUM&MR B1
1,2-Bis(2-methylphenyl)guanidine
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
396.1±45.0 °C at 760 mmHg
[ Melting Point ]:
176-178 °C(lit.)
[ Molecular Formula ]:
C15H17N3
[ Molecular Weight ]:
239.32
[ Flash Point ]:
193.3±28.7 °C
[ Exact Mass ]:
239.142242
[ PSA ]:
47.91000
[ LogP ]:
3.77
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.585
[ Storage condition ]:
Store at RT
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MF1400000
- CHEMICAL NAME :
- Guanidine, 1,3-di-o-tolyl-
- CAS REGISTRY NUMBER :
- 97-39-2
- BEILSTEIN REFERENCE NO. :
- 2653884
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C15-H17-N3
- MOLECULAR WEIGHT :
- 239.35
- WISWESSER LINE NOTATION :
- 1R BMYUM&MR B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IPSTB3 International Polymer Science and Technology. (Rapra Technology Ltd., Shawbury, Shrewsbury, Shropshire SY4 4NR, UK) Volume(issue)/page/year: 3,93,1976
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 120 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- JIDHAN Journal of Industrial Hygiene. (Cambridge, MA) V.1-17, 1919-35. For publisher information, see AEHLAU. Volume(issue)/page/year: 13,87,1931 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81800 No. of Facilities: 157 (estimated) No. of Industries: 5 No. of Occupations: 23 No. of Employees: 3729 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81800 No. of Facilities: 492 (estimated) No. of Industries: 7 No. of Occupations: 18 No. of Employees: 22254 (estimated) No. of Female Employees: 4255 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
UN 2811
[ WGK Germany ]:
3
[ RTECS ]:
MF1400000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2925290090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2925290090
[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
J. Neurosci. Res. 93(2) , 285-95, (2014)
The γ-aminobutyric acid (GABA) type B receptor has been implicated in glial cell development in the peripheral nervous system (PNS), although the exact function of GABA signaling is not known. To inve...
Neurobiol. Aging 36 , 1820-33, (2015)
Apolipoprotein D (apoD) is expressed in the brain and levels are increased in affected brain regions in Alzheimer's disease (AD). The role that apoD may play in regulating AD pathology has not been ad...
J. Sep. Sci. 38 , 2804-12, (2015)
A selective and sensitive method was developed based on dispersive micro-solid-phase extraction for the extraction of hydroquinone, resorcinol, pyrocatechol and phenol from water samples prior to high...