Ethyl lactate

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Names

[ CAS No. ]:
97-64-3

[ Name ]:
Ethyl lactate

[Synonym ]:
(±)-Ethyl 2-hydroxypropionate
QY1&VO2
(±)-Ethyl lactate
Actylol
(±)-Ethyl 2-hydroxypropanoate
Purasolv ELS
FEMA 2440
2-Hydroxypropanoic acid ethyl ester
Ethyl 2-hydroxypropanoate
lactic acid ethyl ester
Acytol
Ethyl α-hydroxypropionate
yl lactate
ethyl 2-hydroxypropionate
Eusolvan
Solactol
MFCD00065359
Ethyl lactate
Ethyl ester of lactic acid
EthyI lactate
Ethyllactat
Propanoic acid, 2-hydroxy-, ethyl ester
dl-ethyl lactate
EINECS 202-598-0

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
154.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-26°C

[ Molecular Formula ]:
C₅H₁₀O₃

[ Molecular Weight ]:
118.131

[ Flash Point ]:
48.9±0.0 °C

[ Exact Mass ]:
118.062996

[ PSA ]:
46.53000

[ LogP ]:
-0.19

[ Vapour Pressure ]:
1.2±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.420

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OD5075000

CHEMICAL NAME :: Lactic acid, ethyl ester

CAS REGISTRY NUMBER :: 97-64-3

BEILSTEIN REFERENCE NO. :: 1209448

LAST UPDATED :: 199701

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C5-H10-O3

MOLECULAR WEIGHT :: 118.15

WISWESSER LINE NOTATION :: QVY1&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,677,1982

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes

REFERENCE :: JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 11,150,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 65,89,1939

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 65,89,1939

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 65,89,1939

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,677,1982

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2605 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 76,189,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1136 No. of Facilities: 41 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 578 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1136 No. of Facilities: 298 (estimated) No. of Industries: 5 No. of Occupations: 23 No. of Employees: 7298 (estimated) No. of Female Employees: 1962 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R10;R37;R41

[ Safety Phrases ]:
S24-S26-S39

[ RIDADR ]:
1192

[ RTECS ]:
OD5075000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2918110000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Calcium lactate
Ethanol
Glycerol
Ethylpyruvate
1,3-Dihydroxyacetone
sucrose
2-hydroxypropionic acid
ethyl 2-[tert-butyl(dimethyl)silyl]oxypropanoate
ETHYLMAGNESIUM BROMIDE
ethyl α-triethylsiloxypropionate

DownStream

Furo[2,3-b]pyridin-3(2H)-one, 2-methyl- (9CI)
n-(2-hydroxyethyl)lactamide
(R)-(+)Lactamide
Ethyl 2-fluoropropionate
(2S)-2-hydroxy-1-morpholin-4-ylpropan-1-one
Ethyl (S)-(-)-2-methoxypropionate
1-Propanone,2-hydroxy-1-(1-piperidinyl)-
5-METHYL-2,4-OXAZOLIDINEDIONE
Urethane

Customs

[ HS Code ]: 2918110000

[ Summary ]:
2918110000. lactic acid, its salts and esters. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

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