Biotin-PEG6-azide

Modify Date: 2024-01-11 06:56:59

Biotin-PEG6-azide Structure
Biotin-PEG6-azide structure
Common Name Biotin-PEG6-azide
CAS Number 1085938-09-5 Molecular Weight 576.71
Density N/A Boiling Point N/A
Molecular Formula C24H44N6O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG6-azide


Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG6-azide

 Biotin-PEG6-azide Biological Activity

Description Biotin-PEG6-azide is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521.

 Chemical & Physical Properties

Molecular Formula C24H44N6O8S
Molecular Weight 576.71