Ravuconazole-d4

Modify Date: 2024-01-16 16:39:45

Ravuconazole-d4 structure	Common Name	Ravuconazole-d4
	CAS Number	1329499-27-5	Molecular Weight	441.49
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₁₃D₄F₂N₅OS	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Ravuconazole-d4

Ravuconazole-d4 (BMS-207147-d4) is the deuterium labeled Ravuconazole. Ravuconazole (BMS-207147) is an orally available triazoleantifungle agent that potently inhibits a wide range of fungi[1][2].

Name	Ravuconazole-d4

Description	Ravuconazole-d4 (BMS-207147-d4) is the deuterium labeled Ravuconazole. Ravuconazole (BMS-207147) is an orally available triazoleantifungle agent that potently inhibits a wide range of fungi[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hata K, et al. In vitro and in vivo antifungal activities of ER-30346, a novel oral triazole with a broad antifungal spectrum.Antimicrob Agents Chemother. 1996 Oct;40(10):2237-42. [3]. Fung-Tomc JC, et al. In vitro activity of a new oral triazole, BMS-207147 (ER-30346)Antimicrob Agents Chemother. 1998 Feb;42(2):313-8. [4]. Hata K, et al. Efficacy of ER-30346, a novel oral triazole antifungal agent, in experimental models of aspergillosis, candidiasis, and cryptococcosis.Antimicrob Agents Chemother. 1996 Oct;40(10):2243-7.

Molecular Formula	C₂₂H₁₃D₄F₂N₅OS
Molecular Weight	441.49