BI 7446

Modify Date: 2024-01-01 00:49:17

BI 7446 structure	Common Name	BI 7446
	CAS Number	2767011-00-5	Molecular Weight	693.52
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₂FN₉O₁₀P₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BI 7446

BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. BI 7446 can activate all five STING variants in cells and induce tumor-specific immune-mediated tumor rejection. BI 7446 can be used for immuno-oncology research[1].

Name	BI 7446

Description	BI 7446 is a cyclic dinucleotide (CDN)-based potent and selective stimulator of interferon genes (STING) agonist. BI 7446 can activate all five STING variants in cells and induce tumor-specific immune-mediated tumor rejection. BI 7446 can be used for immuno-oncology research[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> STING
References	[1]. Kuttruff CA, et al. Discovery of BI 7446: A Potent Cyclic Dinucleotide STING Agonist with Broad-Spectrum Variant Activity for the Treatment of Cancer. J Med Chem. 2023 Jul 27;66(14):9376-9400.

Molecular Formula	C₂₀H₂₂FN₉O₁₀P₂S₂
Molecular Weight	693.52

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BI 7446

Use of BI 7446

Names

BI 7446 Biological Activity

Chemical & Physical Properties