BLU0588

Modify Date: 2024-04-08 16:48:27

BLU0588 structure	Common Name	BLU0588
	CAS Number	2810747-78-3	Molecular Weight	423.51
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₅N₅O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of BLU0588

BLU0588 is an orally active, potent and selective PRKACA (protein kinase cAMP-activated catalytic subunit alpha) kinase inhibitor, with an IC50 of 1 nM and dissociation constant (Kd) of 4 nM. BLU0588 can be used for fibrolamellar carcinoma (FLC) research[1].

Name	BLU0588

Description	BLU0588 is an orally active, potent and selective PRKACA (protein kinase cAMP-activated catalytic subunit alpha) kinase inhibitor, with an IC50 of 1 nM and dissociation constant (Kd) of 4 nM. BLU0588 can be used for fibrolamellar carcinoma (FLC) research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA Signaling Pathways >> Stem Cell/Wnt >> PKA
Target	IC50: 1 nM (PRKACA)[1]
References	[1]. Stefanie S. Schalm, et al. Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma. Gastro Hep Advances. Volume 2, Issue 3, 2023, Pages 307-321.

Molecular Formula	C₂₆H₂₅N₅O
Molecular Weight	423.51

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BLU0588

Use of BLU0588

Names

BLU0588 Biological Activity

Chemical & Physical Properties