bilanafos

Modify Date: 2024-01-05 18:25:04

bilanafos structure	Common Name	bilanafos
	CAS Number	35597-43-4	Molecular Weight	323.28300
	Density	1.33g/cm3	Boiling Point	793.2ºC at 760 mmHg
	Molecular Formula	C₁₁H₂₂N₃O₆P	Melting Point	159-161ºC
	MSDS	N/A	Flash Point	433.5ºC

Use of bilanafos

Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases[1].

Name	bilanafos
Synonym	More Synonyms

Description	Bilanafos is a natural organic phosphine tripeptide antibiotic metabolized by Streptomyces hydroscopius or Streptomyces viridochromeogenes. Bialaphos has antimicrobial activity aganist Gram-negative and positive bacteria as well as some fungal plant diseases[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Takeshi Murakami, et al.The bialaphos biosynthetic genes ofStreptomyces hygroscopicus: Molecular cloning and characterization of the gene cluster. Molecular and General Genetics MGG volume 205, pages42–53 (1986)

Density	1.33g/cm3
Boiling Point	793.2ºC at 760 mmHg
Melting Point	159-161ºC
Molecular Formula	C₁₁H₂₂N₃O₆P
Molecular Weight	323.28300
Flash Point	433.5ºC
Exact Mass	323.12500
PSA	182.29000
Index of Refraction	1.517
Storage condition	Store dry at -4

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AY6826000

CHEMICAL NAME :: L-Alanine, gamma-(hydroxymethylphosphinyl)-L-alpha-aminobutyryl- L-alanyl-

CAS REGISTRY NUMBER :: 35597-43-4

LAST UPDATED :: 199604

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H22-N3-O6-P

MOLECULAR WEIGHT :: 323.33

WISWESSER LINE NOTATION :: QVY1&MVY1&MVYZ2PHO&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),223,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),223,1980

Hazard Codes	Xn
Risk Phrases	R20/21/22
Safety Phrases	26-36

Precursor 4
CAS#:120979-32-0 Bialaphos P-eth... CAS#:120979-33-1 N-L-(2-methyl-2... CAS#:121795-10-6 2-t-butoxycarbo... CAS#:121795-06-0 (9S,12S)-ethyl ...
DownStream 0

(2S)-2-amino-4-(hydroxymethylphosphinyl)butanoyl-L-alanyl-L-alanine

bialaphos

(2S)-2-amino-4-[hydroxy(methyl)phosphinoyl]butyryl-L-alanyl-L-alanine

Bilanafos [ISO]

L-Alanine,4-(hydroxymethylphosphinyl)-L-2-aminobutanoyl-L-alanyl

acide diprogulique

Bialaphos

Antibiotic SF 1293

Phosphinothricylalanylalanine

Bilanafos

(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-[hydroxy(methyl)phosphoryl]butanoyl]amino]propanoyl]amino]propanoic acid

bilanafos

Use of bilanafos

Names

bilanafos Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Precursor & DownStream

Synonyms