BM-PEG3

Modify Date: 2024-01-22 12:00:07

BM-PEG3 structure	Common Name	BM-PEG3
	CAS Number	86099-06-1	Molecular Weight	352.33900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₀N₂O₇	Melting Point	71-72ºC
	MSDS	Chinese USA	Flash Point	N/A

Use of BM-PEG3

BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1,11-Bis(maleimido)tetraethyleneglycol
Synonym	More Synonyms

Description	BM-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Melting Point	71-72ºC
Molecular Formula	C₁₆H₂₀N₂O₇
Molecular Weight	352.33900
Exact Mass	352.12700
PSA	102.45000
Storage condition	-20°C

1,11-Bis-Maleimidodriethyleneglycol