Biochemical Pharmacology 2012-01-01

A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

Grazia Graziani, Simona Artuso, Anastasia De Luca, Alessia Muzi, Dante Rotili, Manuel Scimeca, Maria Grazia Atzori, Claudia Ceci, Antonello Mai, Carlo Leonetti, Lauretta Levati, Elena Bonanno, Lucio Tentori, Anna Maria Caccuri

文献索引：Biochem. Pharmacol. 95 , 16-27, (2015)

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摘要

Nitrobenzoxadiazoles exert antitumor effects against vemurafenib-resistant melanoma cells by sustained activation of different MAPK pathways.

相关化合物

  • 氟化钠
  • AC-DEVD-AFC
  • 3,6-二氧杂-1,8-辛...
  • 曲拉通X-100
  • 替莫唑胺
  • 乙二胺四乙酸

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