Carbohydrate Research 2015-03-20

Carbohydrate conjugation through microwave-assisted functionalization of single-walled carbon nanotubes using perfluorophenyl azides.

Na Kong, Manishkumar R Shimpi, Olof Ramström, Mingdi Yan

文献索引：Carbohydr. Res. 405 , 33-8, (2015)

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摘要

Carbohydrate-functionalized single-walled carbon nanotubes (SWNTs) were synthesized using microwave-assisted reaction of perfluorophenyl azide with the nanotubes. The results showed that microwave radiation provides a rapid and effective means to covalently attach carbohydrates to SWNTs, producing carbohydrate-SWNT conjugates for biorecognition. The carbohydrate-functionalized SWNTs were furthermore shown to interact specifically with cognate carbohydrate-specific proteins (lectins), resulting in predicted recognition patterns. The carbohydrate-presenting SWNTs constitute a new platform for sensitive protein- or cell recognition, which pave the way for glycoconjugated carbon nanomaterials in biorecognition applications. Copyright © 2014 Elsevier Ltd. All rights reserved.

相关化合物

  • 盐酸
  • 叠氮化钠
  • 乙醚
  • 荧光素
  • D-甘露糖
  • 甲醇钠
  • 4-羟乙基哌嗪乙磺酸
  • 三氟化硼乙醚
  • 1-(3-二甲基氨基丙...
  • 五氟苯甲酸甲酯

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