盐酸
一般危化品
盐酸结构式
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常用名 | 盐酸 | 英文名 | Hydrochloric acid |
|---|---|---|---|---|
| CAS号 | 7647-01-0 | 分子量 | 36.461 | |
| 密度 | 1.2 g/mL at 25 °C(lit.) | 沸点 | -84.9±9.0 °C at 760 mmHg | |
| 分子式 | HCl | 熔点 | -35 °C | |
| MSDS | 中文版 美版 | 闪点 | 无意义 | |
| 符号 |
GHS05, GHS07 |
信号词 | Danger |
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Aptamer-based polyvalent ligands for regulated cell attachment on the hydrogel surface.
Biomacromolecules 16(4) , 1382-9, (2015) Natural biomolecules are often used to functionalize materials to achieve desired cell-material interactions. However, their applications can be limited owing to denaturation during the material functionalization process. Therefore, efforts have been made to ... |
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Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.
Biochem. J. 467(2) , 345-52, (2015) Ubiquitylation regulates a multitude of biological processes and this versatility stems from the ability of ubiquitin (Ub) to form topologically different polymers of eight different linkage types. Whereas some linkages have been studied in detail, other link... |
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Small-molecule inhibitors of ERK-mediated immediate early gene expression and proliferation of melanoma cells expressing mutated BRaf.
Biochem. J. 467(3) , 425-38, (2015) Constitutive activation of the extracellular-signal-regulated kinases 1 and 2 (ERK1/2) are central to regulating the proliferation and survival of many cancer cells. The current inhibitors of ERK1/2 target ATP binding or the catalytic site and are therefore l... |
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Fine mapping and characterization of the L-polymerase-binding domain of the respiratory syncytial virus phosphoprotein.
J. Virol. 89(8) , 4421-33, (2015) The minimum requirement for an active RNA-dependent RNA polymerase of respiratory syncytial virus (RSV) is a complex made of two viral proteins, the polymerase large protein (L) and the phosphoprotein (P). Here we have investigated the domain on P that is res... |
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DNase II-dependent DNA digestion is required for DNA sensing by TLR9.
Nat. Commun. 6 , 5853, (2015) DNase II digests DNA in endolysosomes. In the absence of DNase II, undigested DNA activates cytoplasmic DNA-sensing pathways. Little is known, however, about the role of DNase II in endolysosomal DNA sensing by TLR9. Here we show that DNase II is required for... |
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Co-ordinated brain and craniofacial development depend upon Patched1/XIAP regulation of cell survival.
Hum. Mol. Genet. 24(3) , 698-713, (2015) Congenital brain and craniofacial defects often occur together as a consequence of their developmental dependency on common progenitor tissue interactions and signaling pathways during embryogenesis. A classic example of this is perturbation of midline embryo... |
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Diclofenac toxicity in human intestine ex vivo is not related to the formation of intestinal metabolites.
Arch. Toxicol. 89(1) , 107-19, (2015) The use of diclofenac (DCF), a nonsteroidal anti-inflammatory drug, is associated with a high prevalence of gastrointestinal side effects. In vivo studies in rodents suggested that reactive metabolites of DCF produced by the liver or the intestine might be re... |
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Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response.
Eur. J. Pharm. Biopharm. 89 , 30-9, (2015) Novel PEGylated PLA nanocapsules (PEG-AcPLA nanocapsules), loading high percentage of water soluble drugs have been formulated by using multiple emulsion technique without using conventional stabilizers. In particular, sodium deoxycholate hydrate has been use... |
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Mucolipin 1 positively regulates TLR7 responses in dendritic cells by facilitating RNA transportation to lysosomes.
Int. Immunol. 27(2) , 83-94, (2015) Toll-like receptor 7 (TLR7) and TLR9 sense microbial single-stranded RNA (ssRNA) and ssDNA in endolysosomes. Nucleic acid (NA)-sensing in endolysosomes is thought to be important for avoiding TLR7/9 responses to self-derived NAs. Aberrant self-derived NA tran... |
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Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine.
FEBS J. 281(24) , 5498-512, (2014) D-Phosphoglycerate dehydrogenase (PGDH) catalyzes the first committed step of the phosphorylated serine biosynthesis pathway. Here, we report for the first time, the crystal structures of Type IIIK PGDH from Entamoeba histolytica in the apo form, as well as i... |