Toxicology and Industrial Health 2015-07-01

Genotoxic, antigenotoxic and antioxidant properties of methanol extracts obtained from Peltigera horizontalis and Peltigera praetextata.

Gokce Nardemir, Derya Yanmis, Lokman Alpsoy, Medine Gulluce, Guleray Agar, Ali Aslan

文献索引：Toxicol. Ind. Health 31 , 602-13, (2015)

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摘要

Now-a-days, there is a big need to reduce genotoxic effects of mutagenic and carcinogenic agents in environment, which are increased by the technological development. Lichens produce a wide variety of unique metabolites due to being in various extreme areas and being symbiotic organisms of fungi and algae. Therefore, this study was planned to search new sources having antimutagenic activity by researching two different lichen species and to determine whether their usage is safe. With this respect, the mutagenic and antimutagenic properties of methanol extracts of the lichens were determined by the bacterial reverse mutation and sister chromatid exchange assays. Furthermore, the malondialdehyde level, superoxide dismutase, glutathione and glutathione peroxidase activities against aflatoxin B1 were determined for understanding the ways in which the lichens showed their genotoxic properties. © The Author(s) 2013.

相关化合物

  • 叠氮化钠
  • L-色氨酸
  • 氯化钠
  • 甲醇
  • 磷酸氢二钠
  • 4-异丙基甲苯
  • 二甲基亚砜
  • D(+)-无水葡萄糖
  • 硫酸镁
  • 磷酸二氢钠

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