Biochimica et Biophysica Acta 2013-08-01

Ostreopexin: a hemopexin fold protein from the oyster mushroom, Pleurotus ostreatus.

Katja Ota, Miha Mikelj, Tadeja Papler, Adrijana Leonardi, Igor Križaj, Peter Maček

文献索引：Biochim. Biophys. Acta 1834(8) , 1468-73, (2013)

全文：HTML全文

摘要

Proteins with hemopexin repeats are widespread in viruses, prokaryotes and eukaryotes. We report here for the first time the existence of a protein in fungi with the four-bladed β-propeller fold that is typical for hemopexin-like proteins. This protein was isolated from the edible basidiomycetous fungus Pleurotus ostreatus and is named ostreopexin. It binds to Ni(2+)-NTA-agarose, and is structurally and functionally very similar to PA2 albumins isolated from legume seeds and the hemopexin fold protein from rice. Like these plant proteins, ostreopexin shows reversible binding to hemin with moderate affinity, but does not bind to polyamines. We suggest that ostreopexin participates in intracellular management of metal (II or III)-chelates. Copyright © 2013 Elsevier B.V. All rights reserved.

相关化合物

  • 氨三乙酸
  • Hemopexin
  • 氯化血红素

相关文献：

Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.

2015-04-17

[J. Biol. Chem. 290(16) , 10000-17, (2015)]

Cytosolic Hsp60 can modulate proteasome activity in yeast.

2014-10-01

[J. Biol. Chem. 290(6) , 3542-51, (2015)]

Effects of actin-like proteins encoded by two Bacillus pumilus phages on unstable lysogeny, revealed by genomic analysis.

2015-01-01

[Appl. Environ. Microbiol. 81(1) , 339-50, (2014)]

Immune recognition of Onchocerca volvulus proteins in the human host and animal models of onchocerciasis.

2015-05-01

[J. Helminthol. 89(3) , 375-86, (2015)]

Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression.

2014-01-01

[Breast Cancer Res. 16(5) , 433, (2015)]

更多文献...