氨三乙酸结构式
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常用名 | 氨三乙酸 | 英文名 | nitrilotriacetic acid |
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CAS号 | 139-13-9 | 分子量 | 191.139 | |
密度 | 1.6±0.1 g/cm3 | 沸点 | 498.2±40.0 °C at 760 mmHg | |
分子式 | C6H9NO6 | 熔点 | 245 °C (dec.)(lit.) | |
MSDS | 中文版 美版 | 闪点 | 255.1±27.3 °C | |
符号 |
GHS07, GHS08 |
信号词 | Warning |
Analysis of cytochrome P450 CYP119 ligand-dependent conformational dynamics by two-dimensional NMR and X-ray crystallography.
J. Biol. Chem. 290(16) , 10000-17, (2015) Defining the conformational states of cytochrome P450 active sites is critical for the design of agents that minimize drug-drug interactions, the development of isoform-specific P450 inhibitors, and the engineering of novel oxidative catalysts. We used two-di... |
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Cytosolic Hsp60 can modulate proteasome activity in yeast.
J. Biol. Chem. 290(6) , 3542-51, (2015) Hsp60, an essential oligomeric molecular mitochondrial chaperone, has been subject to rigorous basic and clinical research. With yeast as a model system, we provide evidence for the ability of cytosolic yHsp60 to inhibit the yeast proteasome. (i) Following bi... |
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Effects of actin-like proteins encoded by two Bacillus pumilus phages on unstable lysogeny, revealed by genomic analysis.
Appl. Environ. Microbiol. 81(1) , 339-50, (2014) We characterized two newly isolated myoviruses, Bp8p-C and Bp8p-T, infecting the ginger rhizome rot disease pathogen Bacillus pumilus GR8. The plaque of Bp8p-T exhibited a clear center with a turbid rim, suggesting that Bp8p-T could transform into latent phag... |
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Immune recognition of Onchocerca volvulus proteins in the human host and animal models of onchocerciasis.
J. Helminthol. 89(3) , 375-86, (2015) Onchocerca volvulus is a tissue-dwelling, vector-borne nematode parasite of humans and is the causative agent of onchocerciasis or river blindness. Natural infections of BALB/c mice with Litomosoides sigmodontis and of cattle with Onchocerca ochengi were used... |
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Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression.
Breast Cancer Res. 16(5) , 433, (2015) Interleukin-like epithelial-to-mesenchymal transition inducer (ILEI) is an essential cytokine in tumor progression that is upregulated in several cancers, and its altered subcellular localization is a predictor of poor survival in human breast cancer. However... |
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CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization.
J. Lipid Res. 56(1) , 109-21, (2014) CGI-58/ABHD5 coactivates adipose triglyceride lipase (ATGL). In adipocytes, CGI-58 binds to perilipin 1A on lipid droplets under basal conditions, preventing interaction with ATGL. Upon activation of protein kinase A (PKA), perilipin 1A is phosphorylated and ... |
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Effect of immunization against prostate- and testis-expressed (PATE) proteins on sperm function and fecundity in the rat.
J. Reprod. Immunol. 110 , 117-29, (2015) Evaluating the immunocontraceptive potential of sperm-bound proteins is an active area of investigation. In this study, we analyzed the role of prostate- and testes-expressed (PATE) and PATE-F proteins in sperm function. Capacitation was measured as a functio... |
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Phosphoproteomic analysis of the highly-metastatic hepatocellular carcinoma cell line, MHCC97-H.
Int. J. Mol. Sci. 16(2) , 4209-25, (2015) Invasion and metastasis of hepatocellular carcinoma (HCC) is a major cause for lethal liver cancer. Signaling pathways associated with cancer progression are frequently reconfigured by aberrant phosphorylation of key proteins. To capture the key phosphorylati... |
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Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis.
J. Cell Biol. 210(5) , 727-35, (2015) During the G2 to M phase transition, a portion of mitotic regulator Plk1 localizes to the kinetochores and regulates the initiation of kinetochore-microtubule attachments for proper chromosome alignment. Once kinetochore-microtubule attachment is achieved, th... |
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Deficiency of the novel exopolyphosphatase Rv1026/PPX2 leads to metabolic downshift and altered cell wall permeability in Mycobacterium tuberculosis.
MBio 6 , e02428, (2015) Mycobacterium tuberculosis can persist for decades in the human host. Stringent response pathways involving inorganic polyphosphate [poly(P)], which is synthesized and hydrolyzed by polyphosphate kinase (PPK) and exopolyphosphatase (PPX), respectively, are be... |