Organic Letters 2012-01-06

A new biarylphosphine ligand for the Pd-catalyzed synthesis of diaryl ethers under mild conditions.

Luca Salvi, Nicole R Davis, Siraj Z Ali, Stephen L Buchwald

文献索引：Org. Lett. 14(1) , 170-3, (2012)

全文：HTML全文

摘要

A new bulky biarylphosphine ligand (L8) has been developed that allows the Pd-catalyzed C-O cross-coupling of a wide range of aryl halides and phenols under milder conditions than previously possible. A direct correlation between the size of the ligand substituents in the 2', 4', and 6' positions of the nonphosphine containing ring and the reactivity of the derived catalyst system was observed. Specifically, the rate of coupling increased with the size of these substituents.© 2011 American Chemical Society

相关化合物

  • 1-溴-2,4,6-三-叔丁...

相关文献：

Palladium(0)-catalyzed intermolecular amination of unactivated C(sp³)-H bonds.

2011-09-05

[Angew. Chem. Int. Ed. Engl. 50(37) , 8647-51, (2011)]

Rationalizing oligomerization in dimethylindium(III) chalcogenolates (Me2InER') (E = O, S, Se): a structural and computational study.

2010-04-28

[Dalton Trans. 39(16) , 3833-41, (2010)]

The first Cu-and amine-free Sonogashira-type cross-coupling in the C-6-alkynylation of protected 2'-deoxyadenosine. Ngassa FN, et al.

[Tetrahedron 65(21) , 4085-4091, (2009)]

更多文献...