苯甲醛

苯甲醛用途

【用途一】
重要的化工原料，用于制月桂醛、月桂酸、苯乙醛和苯甲酸苄酯等，也用作香料
【用途二】
用作测定臭氧、酚、生物碱和位于羧基旁的亚甲基试剂
【用途三】
可作为特殊的头香香料，微量用于花香配方，如紫丁香、白兰、茉莉、紫罗兰、金合欢、葵花、甜豆花、梅花、橙花等中。香皂中亦可用之。还可作为食用香料用于杏仁、浆果、奶油、樱桃、椰子、杏子、桃子、大胡桃、大李子、香荚兰豆、辛香等香精中。酒用香精如朗姆、白兰地等型中也用之。
【用途四】
苯甲醛是除草剂野燕枯、植物生长调节剂抗倒胺的中间体。
【用途五】
GB 2760--1996规定为暂时允许使用的食用香料。主要用于配制杏仁、樱桃、桃子、果仁等型香精，用量可达40%。作为糖水樱桃罐头的赋香剂，加入量每kg糖水3ml。
【用途六】
医药、染料、香料的中间体。用于生产间氧基苯甲醛、月桂酸、月桂醛、品绿、苯甲酸苄酯、苄叉苯胺、苄叉丙酮等。用以调合皂用香精、食用香精等。
【用途七】
有机合成, 溶剂, 测定臭氧及位于羰基旁边的亚甲基，检定酚和生物碱，香料制备。

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苯甲醛名称

[ CAS 号 ]:
100-52-7

[ 中文名 ]:
苯甲醛

[ 英文名 ]:
Benzaldehyde

[英文别名 ]:

VHR
Benzoylhydride
Benaldehyde
Benzaldehyde
Benzaldehyd
BALD
EINECS 202-860-4
Benzaldehyde,redistilled,AcroSeal
Benzaldehyde [UN1990] [Class 9]
phenylmethanal

苯甲醛物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
178.7±0.0 °C at 760 mmHg

[ 熔点 ]:
-26 °C

[ 分子式 ]:
C₇H₆O

[ 分子量 ]:
106.122

[ 闪点 ]:
62.8±0.0 °C

[ 精确质量 ]:
106.041862

[ PSA ]:
17.07000

[ LogP ]:
1.64

[ 外观性状 ]:
无色液体

[ 蒸汽密度 ]:
3.7 (vs air)

[ 蒸汽压 ]:
1.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.567

[ 储存条件 ]:
包装完整、轻装轻放,库房通风、远离明火、高温、与氧化剂分开存放

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, reducing agents, steam. Air, light and moisture-sensitive.

[ 水溶解性 ]:
<0.01 g/100 mL at 19.5 ºC

[ 凝固点 ]:
-56℃

苯甲醛MSDS

详细MSDS(安全技术说明书)

苯甲醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CU4375000

CHEMICAL NAME :: Benzaldehyde

CAS REGISTRY NUMBER :: 100-52-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 35

MOLECULAR FORMULA :: C7-H6-O

MOLECULAR WEIGHT :: 106.13

WISWESSER LINE NOTATION :: VHR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1300 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - coma

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/m3

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - conjunctive irritation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 28 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LC - Lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/m3

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - conjunctive irritation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Behavioral - tremor Gastrointestinal - ulceration or bleeding from small intestine Kidney, Ureter, Bladder - urine volume increased

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 2020 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9600 mg/kg/16D-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 52 gm/kg/13W-I

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 ppm/6H/14D-C

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in other cell count (unspecified) Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 26 mg/m3/5H/17W-I

TOXIC EFFECTS :: Blood - changes in erythrocyte (RBC) count Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 9600 mg/kg/16D-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 78 gm/kg/13W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 154 gm/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 50 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-HUNGARY:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993 OEL-RUSSIA:STEL 5 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84494 No. of Facilities: 1409 (estimated) No. of Industries: 18 No. of Occupations: 43 No. of Employees: 15976 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84494 No. of Facilities: 3776 (estimated) No. of Industries: 31 No. of Occupations: 58 No. of Employees: 67721 (estimated) No. of Female Employees: 27021 (estimated)

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苯甲醛安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S24

[ 危险品运输编码 ]:
UN 1990 9/PG 3

[ WGK德国 ]:
1

[ RTECS号 ]:
CU4375000

[ 包装等级 ]:
III

[ 危险类别 ]:
9

[ 海关编码 ]:
2912210000

苯甲醛上下游产品

苯甲醛上游产品

苯甲醛下游产品

苯甲醛制备

苯甲醛广泛存在于植物中，特别是在蔷薇科植物中，主要以苷的形式存在于植物的茎皮，叶或种子中，例如苦杏仁中的苦杏仁苷。苯甲醛的工业生产方法主要有两大类：分别以甲苯和苯为原料。实验室制备还可采用催化（钯/硫酸钡）还原苯甲酰氯的方法。 1.甲苯氯化再水解法以甲苯为原料，在光照下进行氯化，得混合氯苄。原料消耗定额：甲苯1700kg/t、氯气3000kg/t、纯碱1500kg/t。 2.苯甲醇氧化法氯苄水解得苯甲醇，再经氧化得苯甲醛。 3.甲苯直接氧化法苯甲醛是甲苯氧化制苯甲酸的中间产物。甲苯→苯甲醇→苯甲醛→苯甲酸。 4.以苯为原料在加压和三氯化铝作用下，苯与一氧化碳和氯化氢反应得。工业品苯甲醛的含量在98.5%以上。其制备方法是以甲苯为原料，在光照下进行氯化得混合氯苄(含C ₆H ₅CH ₂Cl，C ₆H ₅CHCl ₂，C ₆H ₅CCl ₃)，将混合氯苄投入反应釜内，加入少量的氧化锌、磷酸锌混合物催化剂，于125～135℃向搪瓷釜内滴加水，反应随即开始，约10h水加完，反应完毕，在65℃加入纯碱中和，将中和液在水解锅内用纯碱进行水解，回流8h，当油层含侧链氯<0.1%时反应结束，进行水蒸气蒸馏，苯甲醛随水蒸出，进行分层、精馏得产品。 5. 甲苯氯化可得α, α ′- 二氯甲苯，再水解便得到苯甲醛：然后用乙醚萃取，在蒸除乙醚后用亚硫酸氢钠加成精制即可。为制备色谱纯苯甲醛，可以氮气为载气，在装有SE30／白色硅烷化硅藻土担体固定相柱的制备气相色谱仪上注入其粗品，经分离收集其主峰组分，然后装入玻璃安瓿瓶密封即可。 5. 烟草：BU，56；OR，57；BU，14；FC，9， 18；BU，OR，18；FC，BU，OR，40。 6.制法：于装有磁力搅拌器、回流冷凝器、温度计的反应瓶中，加入2,3-二甲基-2-丁基硼烷的THF溶液22.5mL（25mmol），冷至-20℃（CCl4加干冰）。剧烈搅拌下慢慢将5mmol苯甲酸（2）溶于2.5mLTHF并冷至-20℃的溶液加入反应瓶中。10min后，加热回流。在不同的时间取样分析，使生产的醛与2,4-二硝基苯肼反应生成相应的腙，根据腙的量计算醛的收率。12h时收率70%；24h时82%；36h时保持不变。[1]

7.制法：

于装有回流冷凝器（顶部装氯化钙干燥管）、通气导管的已经称重的反应瓶中，加入干燥的甲苯（2）46g（0.5mol），加热至沸。光照下慢慢通入干燥的氯气，直至质量增加39g，而且沸腾温度达到187℃时为止，得到粗品a,a-二氯甲苯（3）。将化合物（3）转移至1.5L反应瓶中，加入500mL水及碳酸钙150g，回流反应4h，同时通入二氧化碳气体以防止生成的苯甲醛氧化。反应结束后，进行水蒸汽蒸馏，直至无油状物馏出^①。将馏出液用乙醚提取三次，合并乙醚层。蒸出乙醚后得粗品苯甲醛。向粗品苯甲醛中慢慢分批加入饱和亚硫酸氢钠溶液，每一次加入后充分摇动。当有结晶性沉淀析出并无苯甲醛的气味时，抽滤。滤饼用乙醚洗涤。将结晶加入过量的碳酸钠溶液中，充分摇动，使苯甲醛游离出来。乙醚提取三次。合并乙醚层，依次用碳酸钠溶液、水洗涤，氯化钙干燥。蒸出乙醚后进行分馏，收集178～180℃的馏分，得苯甲醛（1）36g，收率70%（以甲苯计）。注：①反应液中含有苯甲酸。将热溶液过滤后用盐酸酸化，冷却，可得到片状苯甲酸，mp121℃。

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苯甲醛海关

[ 海关编码 ]: 2912210000

[ 中文概述 ]:
2912210000 苯甲醛。监管条件:无。增值税率:17.0%。退税率:9.0%。最低关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 四聚甲醛报明外观

[ Summary ]:
2912210000 benzaldehyde。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:5.5%。General tariff:30.0%

苯甲醛文献

Olfactometry Profiles and Quantitation of Volatile Sulfur Compounds of Swiss Tilsit Cheeses.

J. Agric. Food Chem. 63 , 7511-21, (2015)

To establish the odor profiles of three differently fabricated commercial Swiss Tilsit cheeses, analyses were conducted using headspace solid-phase microextraction gas chromatography-mass spectrometry...

Poly(vinyl alcohol)-Thioxanthone as One-Component Type II Photoinitiator for Free Radical Polymerization in Organic and Aqueous Media.

Macromol. Rapid Commun. 36 , 923-8, (2015)

A novel one-component type II polymeric photoinitiator, poly(vinyl alcohol)-thioxanthone (PVA-TX), is synthesized by a simple acetalization process and characterized. PVA-TX enables photopolymerizatio...

Ameliorative effect of mepenzolate bromide against pulmonary fibrosis.

J. Pharmacol. Exp. Ther. 350(1) , 79-88, (2014)

Idiopathic pulmonary fibrosis is thought to involve lung injury caused by reactive oxygen species (ROS), which in turn is followed by abnormal fibrosis. A transforming growth factor (TGF)-β1-induced i...

更多文献

苯甲醛

苯甲醛用途

苯甲醛名称

苯甲醛物理化学性质

苯甲醛MSDS

详细MSDS(安全技术说明书)

苯甲醛毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

苯甲醛安全信息

苯甲醛上下游产品

苯甲醛上游产品

苯甲醛下游产品

苯甲醛制备

苯甲醛海关

苯甲醛文献

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