3-氰基吡啶

3-氰基吡啶用途

【用途一】
用作医药、染料中间体
【用途二】
3-氰基吡啶是杀鼠剂灭鼠安、灭鼠腈的中间体，也是医药和饲料中间体。
【用途三】
制药、颜料、树脂等的中间体。
【用途四】
制药、颜料、树脂等的中间体。3-氰基吡啶为重要的化工中间体。在医药工业上主要用于制备外周血管扩张药--烟醇(Nicotinyl alcohol)等。

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3-氰基吡啶名称

[ CAS 号 ]:
100-54-9

[ 中文名 ]:
3-氰基吡啶

[ 英文名 ]:
3-Cyanopyridine

[中文别名 ]:

[英文别名 ]:

pyridine-3-carbonitrile
EINECS 202-863-0
3-Cyanopyridine
MFCD00006372
Pyridine, 3-cyano-
3-Pyridinecarbonitrile
Nicotinonitrile
3-Pyridinenitrile

3-氰基吡啶物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
203.0±13.0 °C at 760 mmHg

[ 熔点 ]:
48-52 °C(lit.)

[ 分子式 ]:
C₆H₄N₂

[ 分子量 ]:
104.109

[ 闪点 ]:
84.4±0.0 °C

[ 精确质量 ]:
104.037445

[ PSA ]:
36.68000

[ LogP ]:
0.50

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
0.3±0.4 mmHg at 25°C

[ 折射率 ]:
1.540

[ 储存条件 ]:
室温

[ 稳定性 ]:
Incompatible with strong oxidizing agents, strong reducing agents, strong acids, strong bases.

[ 水溶解性 ]:
140 g/L (20 ºC)

3-氰基吡啶MSDS

3-氰基吡啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QT3030000

CHEMICAL NAME :: Nicotinonitrile

CAS REGISTRY NUMBER :: 100-54-9

BEILSTEIN REFERENCE NO. :: 0107711

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C6-H4-N2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1185 mg/kg

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: MEPAAX Medycyna Pracy. Industrial Medicine. (Ars-Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1950- Volume(issue)/page/year: 30,109,1979

TYPE OF TEST :: LD25 - Lethal Dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 810 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 64,528,1975

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - corneal damage Skin and Appendages - dermatitis, irritative (after systemic exposure)

REFERENCE :: MEPAAX Medycyna Pracy. Industrial Medicine. (Ars-Polona, POB 1001, 00-068 Warsaw 1, Poland) V.1- 1950- Volume(issue)/page/year: 30,109,1979

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3-氰基吡啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25-S36/37/39-S26

[ 危险品运输编码 ]:
1325.0

[ WGK德国 ]:
3

[ RTECS号 ]:
QT3030000

[ 包装等级 ]:
I; II; III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2933399010

3-氰基吡啶合成路线

3-氰基吡啶上下游产品

3-氰基吡啶上游产品

3-氰基吡啶下游产品

3-氰基吡啶海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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