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丙酮缩甘油

丙酮缩甘油用途

【用途一】
鲨肝醇的中间体。万能溶剂、增塑剂、药用辅料（助溶剂、悬浮剂）。

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丙酮缩甘油名称

[ CAS 号 ]:
100-79-8

[ 中文名 ]:
丙酮缩甘油

[ 英文名 ]:
Solketal

[中文别名 ]:

[英文别名 ]:

(±)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
Solketal
(2,2-Dimethyl-1,3-dioxolan-4-yl)methanol
2,3-(Isopropylidenedioxy)propanol
(±)-2,2-Dimethyl-1,3-dioxolane-4-methanol
1,2-Isopropylidene-rac-glycerol
(RS)-Solketal
2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
1,2-Isopropylideneglycerol
T5O COTJ B1 B1 D1Q

丙酮缩甘油物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
188.5±0.0 °C at 760 mmHg

[ 分子式 ]:
C₆H₁₂O₃

[ 分子量 ]:
132.158

[ 闪点 ]:
80.0±0.0 °C

[ 精确质量 ]:
132.078644

[ PSA ]:
38.69000

[ LogP ]:
0.06

[ 外观性状 ]:
透明无色液体

[ 蒸汽压 ]:
0.2±0.7 mmHg at 25°C

[ 折射率 ]:
1.424

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
miscible

丙酮缩甘油MSDS

丙酮缩甘油毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: JI0400000

CHEMICAL NAME :: 1,3-Dioxolane-4-methanol, 2,2-dimethyl-

CAS REGISTRY NUMBER :: 100-79-8

BEILSTEIN REFERENCE NO. :: 0104465

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C6-H12-O3

MOLECULAR WEIGHT :: 132.18

WISWESSER LINE NOTATION :: T5O COTJ B1 B1 D1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3740 ug/kg

TOXIC EFFECTS :: Cardiac - change in rate Vascular - BP elevation not characterized in autonomic section Vascular - BP lowering not characterized in autonomic section

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 8530 ug/kg

TOXIC EFFECTS :: Cardiac - change in rate Vascular - BP elevation not characterized in autonomic section Vascular - BP lowering not characterized in autonomic section

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

REFERENCE :: TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 21,349,1984

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丙酮缩甘油安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ WGK德国 ]:
2

[ RTECS号 ]:
JI0400000

[ 海关编码 ]:
29329970

丙酮缩甘油合成路线

丙酮缩甘油上下游产品

丙酮缩甘油上游产品

丙酮缩甘油下游产品

丙酮缩甘油制备

用丙三醇与丙酮在氰化氢作用下缩合制得。

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丙酮缩甘油海关

[ 海关编码 ]: 2932999099

[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

丙酮缩甘油文献

Identifying new lignin bioengineering targets: 1. Monolignol-substitute impacts on lignin formation and cell wall fermentability.

BMC Plant Biol. 10 , 114, (2010)

Recent discoveries highlighting the metabolic malleability of plant lignification indicate that lignin can be engineered to dramatically alter its composition and properties. Current plant biotechnolo...

In vitro toxicities of experimental jet fuel system ice-inhibiting agents.

Sci. Total Environ. 274(1-3) , 209-18, (2001)

One research emphasis within the Department of Defense has been to seek the replacement of operational compounds with alternatives that pose less potential risk to human and ecological systems. Altern...

Effects of glycerol acetonide on adrenergic neurotransmission in isolated rabbit heart.

Arzneimittelforschung 42(11) , 1288-91, (1992)

In the present investigation, the solvent glycerol acetonide (GA, CAS 100-79-8) was added (110 mg/min) to the Tyrode buffer perfusing an isolated rabbit heart preloaded with 14C-noradrenaline (NA). GA...

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丙酮缩甘油

丙酮缩甘油用途

丙酮缩甘油名称

丙酮缩甘油物理化学性质

丙酮缩甘油MSDS

详细MSDS(安全技术说明书)

丙酮缩甘油毒性和生态

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

丙酮缩甘油安全信息

丙酮缩甘油合成路线

详细合成路线

丙酮缩甘油上下游产品

丙酮缩甘油上游产品

丙酮缩甘油下游产品

丙酮缩甘油制备

丙酮缩甘油海关

丙酮缩甘油文献

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