奋乃静亚砜
奋乃静亚砜用途
Perphenazine sulfoxide 是 Perphenazine 的亚砜代谢物,由 Perphenazine 氧化形成。
点击显示
奋乃静亚砜名称
[ CAS 号 ]:
10078-25-8
[ 中文名 ]:
奋乃静亚砜
[ 英文名 ]:
Perphenazine sulfoxide
[英文别名 ]:
- etaperazine S-oxide
- Perphenazine Sulfate
- perphenazine sulfoxide
- Perphenazinsulfoxid
- perpherazine sulfoxide
奋乃静亚砜生物活性
[ 描述 ]:
Perphenazine sulfoxide 是 Perphenazine 的亚砜代谢物,由 Perphenazine 氧化形成。
[ 相关类别 ]:
[参考文献]
奋乃静亚砜物理化学性质
[ 密度 ]:
1.41g/cm3
[ 沸点 ]:
624.8ºC at 760mmHg
[ 分子式 ]:
C21H26ClN3O2S
[ 分子量 ]:
419.96800
[ 闪点 ]:
331.7ºC
[ 精确质量 ]:
419.14300
[ PSA ]:
66.23000
[ LogP ]:
3.76470
[ 蒸汽压 ]:
1.78E-16mmHg at 25°C
[ 折射率 ]:
1.71
奋乃静亚砜毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TL7700000
- CHEMICAL NAME :
- 1-Piperazineethanol, 4-(3-(2-chlorophenothiazin-10-yl)propyl)-, sulfoxide
- CAS REGISTRY NUMBER :
- 10078-25-8
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C21-H26-Cl-N3-O2-S
- MOLECULAR WEIGHT :
- 420.01
- WISWESSER LINE NOTATION :
- T C666 BN ISJ EG IO B3- AT6N DNTJ D2Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 127 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 69 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,638,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 68 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 52500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,37,1972
点击显示
奋乃静亚砜安全信息
[ 危险品运输编码 ]:
NONH for all modes of transport
奋乃静亚砜合成路线
奋乃静亚砜上下游产品
奋乃静亚砜上游产品
奋乃静亚砜下游产品
推荐生产厂家/供应商：
相关化合物
【奋乃静亚砜】化源网提供奋乃静亚砜CAS号10078-25-8，奋乃静亚砜MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询奋乃静亚砜上化源网，专业又轻松。>>电脑版：奋乃静亚砜
标题：奋乃静亚砜_用途_密度_沸点_奋乃静亚砜CAS号【10078-25-8】_化源网 地址：https://m.chemsrc.com/mip/cas/10078-25-8_245549.html