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L-750667三盐酸盐

L-750667三盐酸盐用途

L-750,667 TriHydrochloride is a selective D4 dopamine receptor antagonist.

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L-750667三盐酸盐名称

[ CAS 号 ]:
1021868-80-3

[ 中文名 ]:
L-750667三盐酸盐

[ 英文名 ]:
L-750667

[英文别名 ]:

L-750667三盐酸盐物理化学性质

[ 分子式 ]:
C₁₈H₂₂Cl₃IN₄

[ 分子量 ]:
527.65800

[ 精确质量 ]:
525.99500

[ PSA ]:
35.16000

[ LogP ]:
5.89860

L-750667三盐酸盐MSDS

详细MSDS(安全技术说明书)

L-750667三盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P301 + P312 + P330-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

L-750667三盐酸盐文献

Nonconserved residues in the second transmembrane-spanning domain of the D(4) dopamine receptor are molecular determinants of D(4)-selective pharmacology.

Mol. Pharmacol. 57 , 144-152, (2000)

The molecular determinants that govern selective ligand binding to the rat D(4) dopamine receptor were investigated by substituting D(2) dopamine receptor sequences into a D(4) dopamine receptor backg...

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

J. Med. Chem. 39 , 1941, (1996)

Adrenomedullin enhances angiogenic potency of bone marrow transplantation in a rat model of hindlimb ischemia.

Circulation 111 , 356-62, (2005)

Previous studies have shown that adrenomedullin (AM) inhibits vascular endothelial cell apoptosis and induces angiogenesis. We investigated whether AM enhances bone marrow cell-induced angiogenesis.Im...

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