5-氟-2''-脱氧尿苷-5''-单磷酸盐
名称
[ CAS 号 ]:
103226-10-4
[ 中文名 ]:
5-氟-2''-脱氧尿苷-5''-单磷酸盐
[ 英文名 ]:
sodium,[5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate
[英文别名 ]:
- FdUMP
- disodium 5-fluoro-2'-deoxyuridylate
物理化学性质
[ 分子式 ]:
C9H11FN2NaO8P
[ 分子量 ]:
348.15400
[ 精确质量 ]:
348.01300
[ PSA ]:
163.98000
MSDS
安全信息
[ 符号 ]:
GHS07, GHS08
[ 信号词 ]:
Warning
[ 危害声明 ]:
H302-H312-H332-H351
[ 警示性声明 ]:
P280
[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
Xn: Harmful;
[ 风险声明 (欧洲) ]:
20/21/22-40
[ 安全声明 (欧洲) ]:
22-36/37/39
[ 危险品运输编码 ]:
NONH for all modes of transport
文献
PLoS ONE 10(4) , e0123076, (2015)
Biomarkers have revolutionized cancer chemotherapy. However, many biomarker candidates are still in debate. In addition to clinical studies, a priori experimental approaches are needed. Thymidylate sy...
Structures of human thymidylate synthase R163K with dUMP, FdUMP and glutathione show asymmetric ligand binding.Acta Crystallogr. D Biol. Crystallogr. 67 , 60-66, (2011)
Thymidylate synthase (TS) is a well validated target in cancer chemotherapy. Here, a new crystal form of the R163K variant of human TS (hTS) with five subunits per asymmetric part of the unit cell, al...
Novel chemical strategies for thymidylate synthase inhibition.Curr. Med. Chem. 12 , 191-202, (2005)
Thymidylate synthase (TS) is a well-validated target for cancer chemotherapy. TS was established as the principal target of the widely used anticancer drug 5-fluorouracil (5FU). The 5FU metabolite FdU...
推荐生产厂家/供应商:
公司名:上海化源世纪贸易有限公司
区域:上海市普陀区
价格:
联系人:徐经理
公司名:上海吉至生化科技有限公司
区域:上海市奉贤区
价格:
¥9118.0/25mg
¥2378.0/5mg
联系人:刘佳
公司名:上海阿拉丁生化科技股份有限公司
区域:上海市浦东新区
价格:
¥8999.9/100mg
¥1799.9/10mg
¥3599.9/25mg
¥5699.9/50mg
联系人:阿拉丁
产品详情:5-氟-2'-脱氧尿苷-5'-单磷酸盐
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相关化合物
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