那格列奈相关物质C

那格列奈相关物质C名称

[ CAS 号 ]:
105816-06-6

[ 中文名 ]:
那格列奈相关物质C

[ 英文名 ]:
D-Phenylalanine, N-[[4-(1-methylethyl)cyclohexyl]carbonyl]-, cis-

那格列奈相关物质C物理化学性质

[ 分子式 ]:
C19H27NO3

[ 分子量 ]:
317.42300

[ 精确质量 ]:
317.19900

[ PSA ]:
66.40000

[ LogP ]:
3.65180

那格列奈相关物质C安全信息

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
26

[ 危险品运输编码 ]:
NONH for all modes of transport

那格列奈相关物质C文献

Formulation and in vitro evaluation of nateglinide microspheres using HPMC and carbopol-940 polymers by ionic gelation method.

Pak. J. Pharm. Sci. 26(6) , 1229-35, (2013)

This study involves the design and characterization of Nateglinide (NAT) microspheres to enhance patient compliance. Ionic gelation technique was used to prepare Nateglinide Microspheres by using rate...

II. Technological approaches to improve the dissolution behavior of nateglinide, a lipophilic insoluble drug: co-milling.

Int. J. Pharm. 454(1) , 568-72, (2013)

Nateglinide is an oral antidiabetic agent that should be administered 10-30 min before the meal, but it shows low and pH-dependent solubility that may reduce its oral bioavailability. To improve nateg...

I. Technological approaches to improve the dissolution behavior of nateglinide, a lipophilic insoluble drug: nanoparticles and co-mixing.

Int. J. Pharm. 454(1) , 562-7, (2013)

Nateglinide is a non-sulphonylurea insulinotropic oral antidiabetic agent. The main problem in formulating an oral dosage form is its low solubility in aqueous media. This problem is particularly crit...


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