烯丙基缩水甘油醚
烯丙基缩水甘油醚用途
用作聚氨酯橡胶的原料及环氧树脂的稀释剂
【用途二】
分子内既含有碳碳双键又有环氧键，是重要的聚合单体和有机合成中间体。
烯丙基缩水甘油醚名称
[ CAS 号 ]:
106-92-3
[ 中文名 ]:
烯丙基缩水甘油醚
[ 英文名 ]:
Allyl glycidyl ether
[中文别名 ]:
[英文别名 ]:
- 2-[(prop-2-en-1-yloxy)methyl]oxirane
- 3-allyloxy-1,2-epoxypropane
- Glycidyl allyl ether
- Allylglycide ether
- allyloxymethyloxirane
- Ally glycidyl ether
- EINECS 203-442-4
- UNII:HDC0791894
- 1-Allyl-2,3-epoxypropane
- Sipomer AGE
烯丙基缩水甘油醚物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
153.2±15.0 °C at 760 mmHg
[ 熔点 ]:
-100 °C
[ 分子式 ]:
C6H10O2
[ 分子量 ]:
114.142
[ 闪点 ]:
57.2±0.0 °C
[ 精确质量 ]:
114.068077
[ PSA ]:
21.76000
[ LogP ]:
0.78
[ 外观性状 ]:
无色液体
[ 蒸汽密度 ]:
3.9 (vs air)
[ 蒸汽压 ]:
4.3±0.3 mmHg at 25°C
[ 折射率 ]:
1.444
[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开储运
[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, acids, bases. May form peroxides in storage if in contact with air.
[ 水溶解性 ]:
50 g/L (20 ºC)
烯丙基缩水甘油醚MSDS
烯丙基缩水甘油醚毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RR0875000
- CHEMICAL NAME :
- Oxirane, ((2-propenyloxy)methyl)-
- CAS REGISTRY NUMBER :
- 106-92-3
- BEILSTEIN REFERENCE NO. :
- 0105871
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 57
- MOLECULAR FORMULA :
- C6-H10-O2
- MOLECULAR WEIGHT :
- 114.16
- WISWESSER LINE NOTATION :
- T3OTJ B1O2U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1600 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - changes in motor activity (specific assay) Behavioral - ataxia
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 670 ppm/8H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - corneal damage Lungs, Thorax, or Respiration - acute pulmonary edema Gastrointestinal - changes in structure or function of salivary glands
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 390 mg/kg
- TOXIC EFFECTS :
- Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 270 ppm/4H
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - changes in structure or function of salivary glands
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2550 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 ppm/7H/10W-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - emphysema Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 ppm/6H/14D-I
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intramuscular
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg/8D-I
- TOXIC EFFECTS :
- Blood - changes in bone marrow (not otherwise specified) Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 ppm/6H/14D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 ppm/6H/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10 ppm/6H/2Y-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,55,1991 *** REVIEWS *** ACGIH TLV-STEL 47 mg/m3 (10 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 23 mg/m3 (5 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 5 ppm (22 mg/m3) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,9,1971 OSHA PEL (Gen Indu):CL 10 ppm (45 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):CL 10 ppm (45 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):CL 10 ppm (45 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):CL 10 ppm (45 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 ppm (22 mg/m3);STEL 10 ppm (44 mg/m3);Skin JAN 1993 OEL-AUSTRIA:TWA 10 ppm (45 mg/m3) JAN 1993 OEL-BELGIUM:TWA 5 ppm (23 mg/m3);STEL 10 ppm (47 mg/m3);Skin JAN 1993 OEL-DENMARK:STEL 5 ppm (22 mg/m3);Skin JAN 1993 OEL-FINLAND:STEL 5 ppm (22 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 10 ppm (45 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 5 ppm (22 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 10 ppm (45 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 5 ppm (22 mg/m3);STEL 10 ppm (44 mg/m3);Skin JAN 1993 OEL-THAILAND:TWA 10 ppm (45 mg/m3) JAN 1993 OEL-TURKEY:TWA 10 ppm (45 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 5 ppm (22 mg/m3);STEL 10 ppm;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO ALLYL GLYCIDYL ETHER-air:10H TWA 5 ppm;STEL 10 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 04530 No. of Facilities: 153 (estimated) No. of Industries: 9 No. of Occupations: 24 No. of Employees: 2769 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 04530 No. of Facilities: 23 (estimated) No. of Industries: 6 No. of Occupations: 11 No. of Employees: 2457 (estimated) No. of Female Employees: 29 (estimated)
烯丙基缩水甘油醚安全信息
[ 符号 ]:
GHS02, GHS05, GHS07, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H226-H302-H315-H317-H318-H332-H335-H341-H351-H361f-H412
[ 警示性声明 ]:
P261-P273-P280-P305 + P351 + P338
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful;
[ 风险声明 (欧洲) ]:
R10;R20/22;R37/38;R40;R41;R43;R52/53;R62;R68
[ 安全声明 (欧洲) ]:
S24/25-S26-S36/37/39-S61
[ 危险品运输编码 ]:
UN 2219 3/PG 3
[ WGK德国 ]:
3
[ RTECS号 ]:
RR0875000
[ 包装等级 ]:
III
[ 危险类别 ]:
3
[ 海关编码 ]:
2910900090
烯丙基缩水甘油醚合成路线
烯丙基缩水甘油醚上下游产品
烯丙基缩水甘油醚上游产品
烯丙基缩水甘油醚下游产品
烯丙基缩水甘油醚制备
烯丙基缩水甘油醚的制法主要可分为两种。第一种方法是用烯丙醇和环氧氯丙烷为原料，在路易斯酸（H2SO4，BF3·Et2O，HClO4等）的作用下，开环加成得中间体，然后中间体在碱溶液（NaOH溶液等）的作用下脱除HCl闭环而得到产物。反应式如下：
第二种方法是相转移催化法。它是以烯丙醇和环氧氯丙烷为原料，在氢氧化钠溶液和相转移催化剂的作用下反应直接生成烯丙基缩水甘油醚。反应式如下：
烯丙基缩水甘油醚海关
[ 海关编码 ]: 2910900090
[ 中文概述 ]:
2910900090. 三节环环氧化物，环氧醇（酚，醚），包括其卤化，磺化，硝化或亚硝化的衍生物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
烯丙基缩水甘油醚文献
Acta Bioeng. Biomech. 17 , 13-22, (2015)
This paper presents the pilot study aimed at the development of new full interpenetrating polymer networks based on urethane- dimethacrylate and biodegradable epoxy-polyester as the proposition of new...
A polymeric prodrug of 5-fluorouracil-1-acetic acid using a multi-hydroxyl polyethylene glycol derivative as the drug carrier.PLoS ONE 9(11) , e112888, (2014)
Macromolecular prodrugs obtained by covalently conjugating small molecular drugs with polymeric carriers were proven to accomplish controlled and sustained release of the therapeutic agents in vitro a...
In vitro release of model compounds with different hydrophilicity from poly(ester-anhydride) microspheres.Acta Pol. Pharm. 70(6) , 1051-63, (2013)
Poly(ester-anhydride) microspheres were prepared using emulsion solvent evaporation technique from two copolymers obtained by polycondensation of sebacic acid (SBA) and oligo(3-allyloxy-1,2-propylene ...
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公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥165.0/500ml
联系人：刘佳
产品详情：烯丙基缩水甘油醚
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥需询单/1mg
￥需询单/1mg
￥需询单/1g
￥需询单/1mg
联系人：阿拉丁李高志
产品详情：烯丙基缩水甘油醚
公司名：中山市迪欣化工有限公司
区域：中山市三角镇
价格：
￥40.0/1000kg
联系人：王洁
产品详情：烯丙基缩水甘油醚
公司名：济南世纪通达化工有限公司
区域：济南市天桥区
价格：
￥7000.0/190kg
￥33000.0/1ton
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相关化合物
【烯丙基缩水甘油醚】化源网提供烯丙基缩水甘油醚CAS号106-92-3，烯丙基缩水甘油醚MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询烯丙基缩水甘油醚上化源网，专业又轻松。>>电脑版：烯丙基缩水甘油醚
标题：烯丙基缩水甘油醚_MSDS_用途_密度_CAS号【106-92-3】_化源网 地址：https://m.chemsrc.com/mip/cas/106-92-3_118629.html