1-硝基丙烷
1-硝基丙烷用途
主要用作溶剂和中间体，喷气发动机燃料，喷雾剂等。（1）作为溶剂，对醇、酮、醚、酯，以及染料、油脂、蜡、树脂、合成橡胶均有很强的溶解力。与酒精并用是乙酸纤维的强力溶剂；与酒精、芒烃并用可代替氯化烃类溶剂溶解三乙酸纤维。作为低温溶剂可以溶解氯乙烯-乙酸乙烯的共聚物，还可用于溶解硝酸纤维。（2）为胺类、羟胺类、硝基羟基化合物、氯化硝基烷烃等化工产品的中间体，如硝基丙烷与甲烷在硫酸存在下水解，可得硫酸羟胺与丙酸。在医药工业中用于生产抗结核药盐酸乙胺丁酯。
【用途二】
主要用作溶剂和中间体，喷气发动机燃料，喷雾剂等。（1）作为溶剂，对醇；酮；醚；酯，以及染料；油脂；蜡；树脂；合成橡胶均有很强的溶解力。与酒精并用是乙酸纤维的强力溶剂；与酒精；芒烃并用可代替氯化烃类溶剂溶解三乙酸纤维。作为低温溶剂可以溶解氯乙烯-乙酸乙烯的共聚物，还可用于溶解硝酸纤维。（2）为胺类；羟胺类；硝基羟基化合物；氯化硝基烷烃等化工产品的中间体，如硝基丙烷与甲烷在硫酸存在下水解，可得硫酸羟胺与丙酸。在医药工业中用于生产抗结核药盐酸乙胺丁酯。
1-硝基丙烷名称
[ CAS 号 ]:
108-03-2
[ 中文名 ]:
1-硝基丙烷
[ 英文名 ]:
1-Nitropropane
[中文别名 ]:
[英文别名 ]:
- Propane, 1-nitro-
- Propane,1-nitro
- 1-Nitropropane
- 3-nitropropane
- MFCD00007407
- 1-NP
- Nitropropane
- 1-nitro-propane
- EINECS 203-544-9
1-硝基丙烷物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
131.7±3.0 °C at 760 mmHg
[ 熔点 ]:
-108 °C
[ 分子式 ]:
C3H7NO2
[ 分子量 ]:
89.093
[ 闪点 ]:
33.9±0.0 °C
[ 精确质量 ]:
89.047676
[ PSA ]:
45.82000
[ LogP ]:
0.87
[ 外观性状 ]:
无色液体带有一种温和,水果的气味
[ 蒸汽密度 ]:
3.1 (vs air)
[ 蒸汽压 ]:
11.2±0.2 mmHg at 25°C
[ 折射率 ]:
1.399
[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开储运
[ 稳定性 ]:
Stable. Flammable. Incompatible with strong bases, strong oxidizing agents.
[ 水溶解性 ]:
1.40 g/100 mL
1-硝基丙烷MSDS
1-硝基丙烷毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TZ5075000
- CHEMICAL NAME :
- Propane, 1-nitro-
- CAS REGISTRY NUMBER :
- 108-03-2
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 36
- MOLECULAR FORMULA :
- C3-H7-N-O2
- MOLECULAR WEIGHT :
- 89.11
- WISWESSER LINE NOTATION :
- WN3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Human
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 150 ppm
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - conjunctive irritation
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 455 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3100 ppm/8H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 550 mg/kg
- TOXIC EFFECTS :
- Blood - methemoglobinemia-carboxyhemoglobin
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - tremor Behavioral - excitement
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory stimulation
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 5000 ppm/3H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 5000 ppm/3H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Liver
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 221,263,1989 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 91 mg/m3 (25 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 25 ppm (90 mg/m3) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,188,1971 OSHA PEL (Gen Indu):8H TWA 25 ppm (90 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 25 ppm (90 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 25 ppm (90 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 25 ppm (90 mg/m3) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 15 ppm (54 mg/m3) JAN 1993 OEL-FINLAND:TWA 25 ppm (90 mg/m3);STEL 40 ppm (150 mg/m3) JAN 1993 OEL-FRANCE:TWA 25 ppm (90 mg/m3) JAN 1993 OEL-GERMANY:TWA 25 ppm (90 mg/m3) JAN 1993 OEL-THE NETHERLANDS:TWA 25 ppm (90 mg/m3) JAN 1993 OEL-THE PHILIPPINES:TWA 25 ppm (90 mg/m3) JAN 1993 OEL-SWITZERLAND:TWA 25 ppm (90 mg/m3) JAN 1993 OEL-TURKEY:TWA 25 ppm (90 mg/m3) JAN 1993 OEL-UNITED KINGDOM:TWA 25 ppm (90 mg/m3) JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO 1-NITROPROPANE-air:10H TWA 25 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 51100 No. of Facilities: 1155 (estimated) No. of Industries: 20 No. of Occupations: 31 No. of Employees: 9874 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 51100 No. of Facilities: 2539 (estimated) No. of Industries: 19 No. of Occupations: 26 No. of Employees: 21537 (estimated) No. of Female Employees: 1311 (estimated)
1-硝基丙烷安全信息
[ 符号 ]:
GHS02, GHS06
[ 信号词 ]:
Danger
[ 危害声明 ]:
H226-H302 + H312-H331
[ 警示性声明 ]:
P261-P280-P311
[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ 危害码 (欧洲) ]:
Xn:Harmful;
[ 风险声明 (欧洲) ]:
R10;R20/21/22
[ 安全声明 (欧洲) ]:
S9
[ 危险品运输编码 ]:
UN 2608 3/PG 3
[ WGK德国 ]:
1
[ RTECS号 ]:
TZ5075000
[ 包装等级 ]:
III
[ 危险类别 ]:
3
[ 海关编码 ]:
29042000
1-硝基丙烷合成路线
1-硝基丙烷上下游产品
1-硝基丙烷上游产品
1-硝基丙烷下游产品
1-硝基丙烷制备
1.由丙烷经硝化而得。先将丙烷放在预热器内于430-450℃进行预热，然后引入内衬玻璃或二氧化硅的反应塔内。反应塔有几处可向内部丙烷气喷注75%硝酸，反应温度调节到390-440℃，压力0.69-0.86MPa，丙烷与硝酸的摩尔比为5：1，由反应塔出来的气体，经冷凝器冷却，硝基丙烷与稀硝酸即凝缩。而丙烷与气态氧化物则由回收塔回收，丙烷循环使用。所得产品为硝基甲烷10%-30%，硝基乙烷20%-25%，1-硝基丙烷25%，2-硝基丙烷40%。该品也可经丙烯硝化得到。
2.由丙烯等不饱和烃经气相或液相硝化，或饱和烃液相硝化亦可制得硝基丙烷。
1-硝基丙烷海关
[ 海关编码 ]: 2904209090
[ 中文概述 ]:
2904209090 其他仅含硝基或亚硝基的衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2904209090 derivatives containing only nitro or only nitroso groups。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
1-硝基丙烷文献
J. Chromatogr. A. 1410 , 1-8, (2015)
In this work, a highly reproducible standard gas generating vial is proposed. The vial is comprised of a silicon diffusion pump oil spiked with an appropriate calibration compound, such as modified Mc...
Performance of graphene sheets as stationary phase for capillary gas chromatographic separations.J. Chromatogr. A. 1399 , 74-9, (2015)
This work presents the investigation of graphene as a new type of stationary phase for capillary GC separations. Graphene capillary column (0.25 mm, i.d.) achieved column efficiency of 3100 plates/m d...
Spin trapping of nitric oxide by aci anions of nitroalkanes.Nitric Oxide 10(2) , 53-9, (2004)
In alkaline solutions, nitroalkanes (RCH2NO2) undergo deprotonation and rearrange to an aci anion (RHC=NO2-), which may function as a spin trap. Using electron paramagnetic resonance (EPR) spectroscop...
推荐生产厂家/供应商：
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥288.0/500ml
￥98.0/100ml
联系人：刘佳
产品详情：1-硝基丙烷
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥需询单/1mg
￥需询单/1mg
￥需询单/1mg
￥需询单/1mg
联系人：阿拉丁李高志
产品详情：1-硝基丙烷
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